Huang H - Search Results

1

Manipulating the Click Reactivity of Dibenzoazacyclooctynes: From Azide Click Component to Caged Acylation Reagent by Silver Catalysis.

Shi W, Tang F, Ao J, Yu Q, Liu J, Tang Y, Jiang B, Ren X, Huang H, Yang W, Huang W. Shi W, et al. Among authors: huang h, huang w. Angew Chem Int Ed Engl. 2020 Nov 2;59(45):19940-19944. doi: 10.1002/anie.202009408. Epub 2020 Aug 31. Angew Chem Int Ed Engl. 2020. PMID: 32697885

2

Discovery of a potent, selective, and covalent ZAP-70 kinase inhibitor.

Rao D, Li H, Ren X, Sun Y, Wen C, Zheng M, Huang H, Tang W, Xu S. Rao D, et al. Among authors: huang h. Eur J Med Chem. 2021 Jul 5;219:113393. doi: 10.1016/j.ejmech.2021.113393. Epub 2021 Mar 30. Eur J Med Chem. 2021. PMID: 33845236

3

Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine.

Xue Y, Ren X, Zhu Z, Lei P, Liu M, Wan M, Zhong D, Huang H, Diao X. Xue Y, et al. Among authors: huang h. Life Sci. 2021 Dec 15;287:120125. doi: 10.1016/j.lfs.2021.120125. Epub 2021 Nov 8. Life Sci. 2021. PMID: 34762904

4

Quantitative Proteomics Analysis Expands the Roles of Lysine β-Hydroxybutyrylation Pathway in Response to Environmental β-Hydroxybutyrate.

Hou W, Liu G, Ren X, Liu X, He L, Huang H. Hou W, et al. Among authors: huang h. Oxid Med Cell Longev. 2022 Feb 24;2022:4592170. doi: 10.1155/2022/4592170. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 35251473 Free PMC article.

5

Discovery of a selective and covalent small-molecule inhibitor of BFL-1 protein that induces robust apoptosis in cancer cells.

Feng X, Yan Z, Zhou F, Lou J, Lyu X, Ren X, Zeng Z, Liu C, Zhang S, Zhu D, Huang H, Yang J, Zhao Y. Feng X, et al. Among authors: huang h. Eur J Med Chem. 2022 Jun 5;236:114327. doi: 10.1016/j.ejmech.2022.114327. Epub 2022 Mar 29. Eur J Med Chem. 2022. PMID: 35385805

6

A Traceless Site-Specific Conjugation on Native Antibodies Enables Efficient One-Step Payload Assembly.

Zeng Y, Shi W, Dong Q, Li W, Zhang J, Ren X, Tang C, Liu B, Song Y, Wu Y, Diao X, Zhou H, Huang H, Tang F, Huang W. Zeng Y, et al. Among authors: huang h, huang w. Angew Chem Int Ed Engl. 2022 Sep 5;61(36):e202204132. doi: 10.1002/anie.202204132. Epub 2022 Jul 27. Angew Chem Int Ed Engl. 2022. PMID: 35737596

7

Quantitative Proteomics Explore the Potential Targets and Action Mechanisms of Hydroxychloroquine.

Zhao J, Zhao Z, Hou W, Jiang Y, Liu G, Ren X, Liu K, Liu H, Chen K, Huang H. Zhao J, et al. Among authors: huang h. Molecules. 2022 Aug 14;27(16):5175. doi: 10.3390/molecules27165175. Molecules. 2022. PMID: 36014414 Free PMC article.

8

Chemo- and Site-Selective Lysine Modification of Peptides and Proteins under Native Conditions Using the Water-Soluble Zolinium.

Sun H, Xi M, Jin Q, Zhu Z, Zhang Y, Jia G, Zhu G, Sun M, Zhang H, Ren X, Zhang Y, Xu Z, Huang H, Shen J, Li B, Ge G, Chen K, Zhu W. Sun H, et al. Among authors: huang h. J Med Chem. 2022 Sep 8;65(17):11840-11853. doi: 10.1021/acs.jmedchem.2c00937. Epub 2022 Aug 22. J Med Chem. 2022. PMID: 36073068

9

Selective degradation of cellular BRD3 and BRD4-L promoted by PROTAC molecules in six cancer cell lines.

Yan Z, Lyu X, Lin D, Wu G, Gong Y, Ren X, Xiao J, Lou J, Huang H, Chen Y, Zhao Y. Yan Z, et al. Among authors: huang h. Eur J Med Chem. 2023 Jun 5;254:115381. doi: 10.1016/j.ejmech.2023.115381. Epub 2023 Apr 14. Eur J Med Chem. 2023. PMID: 37084596

10

HDAC1/2/3 are major histone desuccinylases critical for promoter desuccinylation.

Li J, Lu L, Liu L, Ren X, Chen J, Yin X, Xiao Y, Li J, Wei G, Huang H, Wei W, Wong J. Li J, et al. Among authors: huang h. Cell Discov. 2023 Aug 15;9(1):85. doi: 10.1038/s41421-023-00573-9. Cell Discov. 2023. PMID: 37580347 Free PMC article.

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