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Gout and pseudo-gout-related crystals promote GLUT1-mediated glycolysis that governs NLRP3 and interleukin-1β activation on macrophages.
Renaudin F, Orliaguet L, Castelli F, Fenaille F, Prignon A, Alzaid F, Combes C, Delvaux A, Adimy Y, Cohen-Solal M, Richette P, Bardin T, Riveline JP, Venteclef N, Lioté F, Campillo-Gimenez L, Ea HK. Renaudin F, et al. Among authors: alzaid f. Ann Rheum Dis. 2020 Nov;79(11):1506-1514. doi: 10.1136/annrheumdis-2020-217342. Epub 2020 Jul 22. Ann Rheum Dis. 2020. PMID: 32699039
Soybean oil-based HFD induces gut dysbiosis that leads to steatosis, hepatic inflammation and insulin resistance in mice.
Jacob T, Sindhu S, Hasan A, Malik MZ, Arefanian H, Al-Rashed F, Nizam R, Kochumon S, Thomas R, Bahman F, Shenouda S, Wilson A, Akther N, Al-Roub A, Abukhalaf N, Albeloushi S, Abu-Farha M, Al Madhoun A, Alzaid F, Thanaraj TA, Koistinen HA, Tuomilehto J, Al-Mulla F, Ahmad R. Jacob T, et al. Among authors: alzaid f. Front Microbiol. 2024 Aug 6;15:1407258. doi: 10.3389/fmicb.2024.1407258. eCollection 2024. Front Microbiol. 2024. PMID: 39165573 Free PMC article.
Glucose intolerance induces anxiety-like behaviors independent of obesity and insulin resistance in a novel model of nutritional metabolic stress.
Al-Onaizi M, Braysh K, Alkafeef SS, Altarrah D, Dannoon S, Alasousi D, Adel H, Al-Ajmi M, Kandari A, Najem R, Nizam R, Williams MR, John S, Thanaraj TA, Ahmad R, Al-Hussaini H, Al-Mulla F, Alzaid F. Al-Onaizi M, et al. Among authors: alzaid f. Nutr Neurosci. 2024 Oct;27(10):1143-1161. doi: 10.1080/1028415X.2024.2310419. Epub 2024 Feb 6. Nutr Neurosci. 2024. PMID: 38319634 Free article.
Glucagon-like Peptide 1 Receptor Agonists, Diabetic Retinopathy and Angiogenesis: The AngioSafe Type 2 Diabetes Study.
Gaborit B, Julla JB, Besbes S, Proust M, Vincentelli C, Alos B, Ancel P, Alzaid F, Garcia R, Mailly P, Sabatier F, Righini M, Gascon P, Matonti F, Houssays M, Goumidi L, Vignaud L, Guillonneau X, Erginay A, Dupas B, Marie-Louise J, Autié M, Vidal-Trecan T, Riveline JP, Venteclef N, Massin P, Muller L, Dutour A, Gautier JF, Germain S. Gaborit B, et al. Among authors: alzaid f. J Clin Endocrinol Metab. 2020 Apr 1;105(4):dgz069. doi: 10.1210/clinem/dgz069. J Clin Endocrinol Metab. 2020. PMID: 31589290 Clinical Trial.
Mechanisms of Macrophage Polarization in Insulin Signaling and Sensitivity.
Orliaguet L, Dalmas E, Drareni K, Venteclef N, Alzaid F. Orliaguet L, et al. Among authors: alzaid f. Front Endocrinol (Lausanne). 2020 Feb 19;11:62. doi: 10.3389/fendo.2020.00062. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 32140136 Free PMC article. Review.
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