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Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention.
Adv Drug Deliv Rev. 2020;159:245-293. doi: 10.1016/j.addr.2020.07.013. Epub 2020 Jul 23.
Adv Drug Deliv Rev. 2020.
PMID: 32711004
Free PMC article.
Review.
Fatty Acids and Breast Cancer: Make Them on Site or Have Them Delivered.
Kinlaw WB, Baures PW, Lupien LE, Davis WL, Kuemmerle NB.
Kinlaw WB, et al. Among authors: lupien le.
J Cell Physiol. 2016 Oct;231(10):2128-41. doi: 10.1002/jcp.25332. Epub 2016 Feb 16.
J Cell Physiol. 2016.
PMID: 26844415
Free PMC article.
Review.
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Endocytosis of very low-density lipoproteins: an unexpected mechanism for lipid acquisition by breast cancer cells.
Lupien LE, Bloch K, Dehairs J, Traphagen NA, Feng WW, Davis WL, Dennis T, Swinnen JV, Wells WA, Smits NC, Kuemmerle NB, Miller TW, Kinlaw WB.
Lupien LE, et al.
J Lipid Res. 2020 Feb;61(2):205-218. doi: 10.1194/jlr.RA119000327. Epub 2019 Dec 5.
J Lipid Res. 2020.
PMID: 31806729
Free PMC article.
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Lipogenesis and lipolysis: the pathways exploited by the cancer cells to acquire fatty acids.
Zaidi N, Lupien L, Kuemmerle NB, Kinlaw WB, Swinnen JV, Smans K.
Zaidi N, et al.
Prog Lipid Res. 2013 Oct;52(4):585-9. doi: 10.1016/j.plipres.2013.08.005. Epub 2013 Aug 31.
Prog Lipid Res. 2013.
PMID: 24001676
Free PMC article.
Review.
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Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1.
Moyer BJ, Rojas IY, Kerley-Hamilton JS, Hazlett HF, Nemani KV, Trask HW, West RJ, Lupien LE, Collins AJ, Ringelberg CS, Gimi B, Kinlaw WB 3rd, Tomlinson CR.
Moyer BJ, et al. Among authors: lupien le.
Toxicol Appl Pharmacol. 2016 Jun 1;300:13-24. doi: 10.1016/j.taap.2016.03.011. Epub 2016 Mar 25.
Toxicol Appl Pharmacol. 2016.
PMID: 27020609
Free PMC article.
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An Inhibitor of Fatty Acid Synthase Thioesterase Domain with Improved Cytotoxicity against Breast Cancer Cells and Stability in Plasma.
Lupien LE, Dunkley EM, Maloy MJ, Lehner IB, Foisey MG, Ouellette ME, Lewis LD, Pooler DB, Kinlaw WB, Baures PW.
Lupien LE, et al.
J Pharmacol Exp Ther. 2019 Oct;371(1):171-185. doi: 10.1124/jpet.119.258947. Epub 2019 Jul 12.
J Pharmacol Exp Ther. 2019.
PMID: 31300609
Free PMC article.
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PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation.
Khadka P, Reitman ZJ, Lu S, Buchan G, Gionet G, Dubois F, Carvalho DM, Shih J, Zhang S, Greenwald NF, Zack T, Shapira O, Pelton K, Hartley R, Bear H, Georgis Y, Jarmale S, Melanson R, Bonanno K, Schoolcraft K, Miller PG, Condurat AL, Gonzalez EM, Qian K, Morin E, Langhnoja J, Lupien LE, Rendo V, Digiacomo J, Wang D, Zhou K, Kumbhani R, Guerra Garcia ME, Sinai CE, Becker S, Schneider R, Vogelzang J, Krug K, Goodale A, Abid T, Kalani Z, Piccioni F, Beroukhim R, Persky NS, Root DE, Carcaboso AM, Ebert BL, Fuller C, Babur O, Kieran MW, Jones C, Keshishian H, Ligon KL, Carr SA, Phoenix TN, Bandopadhayay P.
Khadka P, et al. Among authors: lupien le.
Nat Commun. 2022 Feb 1;13(1):604. doi: 10.1038/s41467-022-28198-8.
Nat Commun. 2022.
PMID: 35105861
Free PMC article.
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