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Route of 41BB/41BBL Costimulation Determines Effector Function of B7-H3-CAR.CD28ζ T Cells.
Nguyen P, Okeke E, Clay M, Haydar D, Justice J, O'Reilly C, Pruett-Miller S, Papizan J, Moore J, Zhou S, Throm R, Krenciute G, Gottschalk S, DeRenzo C. Nguyen P, et al. Mol Ther Oncolytics. 2020 Jun 23;18:202-214. doi: 10.1016/j.omto.2020.06.018. eCollection 2020 Sep 25. Mol Ther Oncolytics. 2020. PMID: 32728609 Free PMC article.
Midkine Attenuates Aβ Fibril Assembly and AmyloidPlaque Formation.
Peng J, Zaman M, Yang S, Huang Y, Yarbro J, Wang Z, Liu D, Soliman H, Hemphill A, Harvey S, Pruett-Miller S, Stewart V, Tanwar A, Kalathur R, Grace C, Turk M, Chittori S, Jiao Y, Wu Z, High A, Wang X, Serrano G, Beach T, Yu G, Yang Y, Chen PC. Peng J, et al. Res Sq [Preprint]. 2024 Jun 7:rs.3.rs-4361125. doi: 10.21203/rs.3.rs-4361125/v1. Res Sq. 2024. PMID: 38883748 Free PMC article. Preprint.
Profiling chromatin accessibility in pediatric acute lymphoblastic leukemia identifies subtype-specific chromatin landscapes and gene regulatory networks.
Diedrich JD, Dong Q, Ferguson DC, Bergeron BP, Autry RJ, Qian M, Yang W, Smith C, Papizan JB, Connelly JP, Hagiwara K, Crews KR, Pruett-Miller SM, Pui CH, Yang JJ, Relling MV, Evans WE, Savic D. Diedrich JD, et al. Leukemia. 2021 Nov;35(11):3078-3091. doi: 10.1038/s41375-021-01209-1. Epub 2021 Mar 13. Leukemia. 2021. PMID: 33714976 Free PMC article.
Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators.
Nishiguchi G, Keramatnia F, Min J, Chang Y, Jonchere B, Das S, Actis M, Price J, Chepyala D, Young B, McGowan K, Slavish PJ, Mayasundari A, Jarusiewicz JA, Yang L, Li Y, Fu X, Garrett SH, Papizan JB, Kodali K, Peng J, Pruett Miller SM, Roussel MF, Mullighan C, Fischer M, Rankovic Z. Nishiguchi G, et al. J Med Chem. 2021 Jun 10;64(11):7296-7311. doi: 10.1021/acs.jmedchem.0c01313. Epub 2021 May 27. J Med Chem. 2021. PMID: 34042448 Free PMC article.
SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents.
Gartrell J, Mellado-Largarde M, Clay MR, Bahrami A, Sahr NA, Sykes A, Blankenship K, Hoffmann L, Xie J, Cho HP, Twarog N, Connelly M, Yan KK, Yu J, Porter SN, Pruett-Miller SM, Neale G, Tinkle CL, Federico SM, Stewart EA, Shelat AA. Gartrell J, et al. Mol Cancer Ther. 2021 Nov;20(11):2151-2165. doi: 10.1158/1535-7163.MCT-21-0089. Epub 2021 Aug 19. Mol Cancer Ther. 2021. PMID: 34413129 Free PMC article.
Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity.
Prinzing B, Zebley CC, Petersen CT, Fan Y, Anido AA, Yi Z, Nguyen P, Houke H, Bell M, Haydar D, Brown C, Boi SK, Alli S, Crawford JC, Riberdy JM, Park JJ, Zhou S, Velasquez MP, DeRenzo C, Lazzarotto CR, Tsai SQ, Vogel P, Pruett-Miller SM, Langfitt DM, Gottschalk S, Youngblood B, Krenciute G. Prinzing B, et al. Sci Transl Med. 2021 Nov 17;13(620):eabh0272. doi: 10.1126/scitranslmed.abh0272. Epub 2021 Nov 17. Sci Transl Med. 2021. PMID: 34788079 Free PMC article.
154 results