Zhao Y - Search Results

1

Pharmacokinetics, pharmacodynamics, and tolerability of JY09 in healthy Chinese subjects: A titrating, dose-escalating study.

Yang G, Cao B, Yang Y, Geng Y, Lin H, Jiang J, Zhao Y, Weng Z, Zhang C, Bai Y, Li J. Yang G, et al. Among authors: zhao y. Int J Clin Pharmacol Ther. 2020 Nov;58(11):608-616. doi: 10.5414/CP203730. Int J Clin Pharmacol Ther. 2020. PMID: 32729820 Clinical Trial.

2

SHR2285, the first selectively oral FXIa inhibitor in China: Safety, tolerability, pharmacokinetics and pharmacodynamics combined with aspirin, clopidogrel or ticagrelor.

Ma T, Dong Y, Huang L, Yang Y, Geng Y, Fei F, Xie P, Zhao Y, Lin H, Yang Z, Jin Y, Ju X, Sun R, Li J. Ma T, et al. Among authors: zhao y. Front Pharmacol. 2022 Oct 19;13:1027627. doi: 10.3389/fphar.2022.1027627. eCollection 2022. Front Pharmacol. 2022. PMID: 36339534 Free PMC article.

3

First-in-human study to assess the safety, tolerability, pharmacokinetics and immunogenicity of DS002, an anti-nerve growth factor monoclonal antibody.

Ma T, Cao B, Huang L, Yang Y, Geng Y, Xie P, Zhao Y, Lin H, Wang K, Wang C, Sun R, Li J. Ma T, et al. Among authors: zhao y. Front Pharmacol. 2022 Dec 12;13:1075309. doi: 10.3389/fphar.2022.1075309. eCollection 2022. Front Pharmacol. 2022. PMID: 36578547 Free PMC article.

4

Metabolomics analysis reveals cytotoxic effects of ouabain towards psoriatic keratinocytes via impairment of glutathione metabolism.

Zhou X, Fei F, Song W, Ma H, Xu Z, Yue J, Cao B, Sun R, Zhao Y, Yang Y, Jiang J, Geng Y, Weng Z, Li J. Zhou X, et al. Among authors: zhao y. Mol Genet Genomics. 2023 May;298(3):567-577. doi: 10.1007/s00438-023-02001-9. Epub 2023 Mar 1. Mol Genet Genomics. 2023. PMID: 36856826 Free PMC article.

5

Mesenchymal stromal cells promote the drug resistance of gastrointestinal stromal tumors by activating the PI3K-AKT pathway via TGF-β2.

Zhao Y, Weng Z, Zhou X, Xu Z, Cao B, Wang B, Li J. Zhao Y, et al. J Transl Med. 2023 Mar 25;21(1):219. doi: 10.1186/s12967-023-04063-0. J Transl Med. 2023. PMID: 36966336 Free PMC article.

6

Phase 1 study to evaluate the effects of rifampin or itraconazole on the pharmacokinetics of limertinib (ASK120067), a novel mutant-selective inhibitor of the epidermal growth factor receptor in healthy Chinese subjects.

Cao B, Huang L, Liu M, Lin H, Ma T, Zhao Y, Geng Y, Yang Y, Guo H, Li J. Cao B, et al. Among authors: zhao y. Expert Opin Drug Metab Toxicol. 2023 Sep;19(9):653-664. doi: 10.1080/17425255.2023.2260738. Epub 2023 Oct 12. Expert Opin Drug Metab Toxicol. 2023. PMID: 37811634 Clinical Trial.

7

The effect of food on the pharmacokinetics of Sutetinib maleate capsule, an irreversible EGFR tyrosine kinase inhibitor, in healthy Chinese subjects.

Cao B, Ma T, Zhang Y, Huang L, Lin H, Jiang H, Zhao Y, Geng Y, Yang Y, Cao S, Li J. Cao B, et al. Among authors: zhao y. Invest New Drugs. 2024 Jun;42(3):289-298. doi: 10.1007/s10637-024-01436-0. Epub 2024 Apr 11. Invest New Drugs. 2024. PMID: 38602625 Clinical Trial.

8

The first selective VAP-1 inhibitor in China, TT-01025-CL: safety, tolerability, pharmacokinetics, and pharmacodynamics of single- and multiple-ascending doses.

Yang Y, Yu L, Sheng Z, Lin H, Weng Z, Song W, Cao B, Zhao Y, Gao Y, Ni S, Wang H, Ma T, Huang L, Sun C, Li J. Yang Y, et al. Among authors: zhao y. Front Pharmacol. 2024 Apr 29;15:1327008. doi: 10.3389/fphar.2024.1327008. eCollection 2024. Front Pharmacol. 2024. PMID: 38741586 Free PMC article.

9

Antagonizing Effects of Chromium Against Iron-Decreased Glucose Uptake by Regulating ROS-Mediated PI3K/Akt/GLUT4 Signaling Pathway in C2C12.

Fan L, Li L, Zhao Y, Zhao Y, Wang F, Wang Q, Ma Z, He S, Qiu J, Zhang J, Li J, Chang Z, Zhang Y. Fan L, et al. Among authors: zhao y. Biol Trace Elem Res. 2024 Feb;202(2):701-712. doi: 10.1007/s12011-023-03695-z. Epub 2023 May 8. Biol Trace Elem Res. 2024. PMID: 37156991

10

A family with normal sperm motility carrying a sY86 deletion in AZFa region and partial deletion in AZFc region.

Zhao Y, Zhi W, Xiong D, Li N, Du X, Zeng J, Zhang G, Liu W. Zhao Y, et al. Front Genet. 2025 Jan 9;15:1519774. doi: 10.3389/fgene.2024.1519774. eCollection 2024. Front Genet. 2025. PMID: 39850494 Free PMC article.

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