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Mitoxantrone, pixantrone and mitoxantrone (2-hydroxyethyl)piperazine are toll-like receptor 4 antagonists, inhibit NF-κB activation, and decrease TNF-alpha secretion in primary microglia.
Rinne M, Mätlik K, Ahonen T, Vedovi F, Zappia G, Moreira VM, Yli-Kauhaluoma J, Leino S, Salminen O, Kalso E, Airavaara M, Xhaard H. Rinne M, et al. Eur J Pharm Sci. 2020 Nov 1;154:105493. doi: 10.1016/j.ejps.2020.105493. Epub 2020 Jul 27. Eur J Pharm Sci. 2020. PMID: 32730846 Free article.
Corrigendum to "Prolyl oligopeptidase inhibition by KYP-2407 increases alpha-synuclein fibril degradation in neuron-like cells" [Biomed. Pharmacother. 131 (2020) 110788].
Rostami J, Jäntti M, Cui H, Rinne MK, Kukkonen JP, Falk A, Erlandsson A, Myöhänen T. Rostami J, et al. Among authors: rinne mk. Biomed Pharmacother. 2021 Jan;133:111019. doi: 10.1016/j.biopha.2020.111019. Epub 2020 Nov 24. Biomed Pharmacother. 2021. PMID: 33246737 Free article. No abstract available.
119 results