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From proof of concept to the routine use of an automated and robust multi-dimensional liquid chromatography mass spectrometry workflow applied for the charge variant characterization of therapeutic antibodies.
Goyon A, Dai L, Chen T, Wei B, Yang F, Andersen N, Kopf R, Leiss M, Mølhøj M, Guillarme D, Stella C. Goyon A, et al. Among authors: stella c. J Chromatogr A. 2020 Mar 29;1615:460740. doi: 10.1016/j.chroma.2019.460740. Epub 2019 Nov 27. J Chromatogr A. 2020. PMID: 31796250
Discovery of a dual pathway aggregation mechanism for a therapeutic constrained peptide.
Chen T, Tang S, Hecht ES, Yen CW, Andersen N, Chin S, Cadang L, Roper B, Estevez A, Rohou A, Chang D, Dai L, Liu P, Al-Sayah M, Nagapudi K, Lin F, Famili A, Hu C, Kuhn R, Stella C, Crittenden CM, Gruenhagen JA, Venkatramani C, Hannoush RN, Leung D, Vandlen R, Yehl P. Chen T, et al. Among authors: stella c. J Pharm Sci. 2021 Jun;110(6):2362-2371. doi: 10.1016/j.xphs.2020.12.041. Epub 2021 Feb 27. J Pharm Sci. 2021. PMID: 33652014
Inter-laboratory study to evaluate the performance of automated online characterization of antibody charge variants by multi-dimensional LC-MS/MS.
Camperi J, Grunert I, Heinrich K, Winter M, Özipek S, Hoelterhoff S, Weindl T, Mayr K, Bulau P, Meier M, Mølhøj M, Leiss M, Guillarme D, Bathke A, Stella C. Camperi J, et al. Among authors: stella c. Talanta. 2021 Nov 1;234:122628. doi: 10.1016/j.talanta.2021.122628. Epub 2021 Jun 18. Talanta. 2021. PMID: 34364437
183 results