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A Photoaffinity-Based Fragment-Screening Platform for Efficient Identification of Protein Ligands.
Grant EK, Fallon DJ, Hann MM, Fantom KGM, Quinn C, Zappacosta F, Annan RS, Chung CW, Bamborough P, Dixon DP, Stacey P, House D, Patel VK, Tomkinson NCO, Bush JT. Grant EK, et al. Among authors: bush jt. Angew Chem Int Ed Engl. 2020 Nov 16;59(47):21096-21105. doi: 10.1002/anie.202008361. Epub 2020 Sep 7. Angew Chem Int Ed Engl. 2020. PMID: 32745361 Free article.
A Turing Test for Molecular Generators.
Bush JT, Pogany P, Pickett SD, Barker M, Baxter A, Campos S, Cooper AWJ, Hirst D, Inglis G, Nadin A, Patel VK, Poole D, Pritchard J, Washio Y, White G, Green DVS. Bush JT, et al. J Med Chem. 2020 Oct 22;63(20):11964-11971. doi: 10.1021/acs.jmedchem.0c01148. Epub 2020 Oct 12. J Med Chem. 2020. PMID: 32955254
One-Step Synthesis of Photoaffinity Probes for Live-Cell MS-Based Proteomics.
Fallon DJ, Lehmann S, Chung CW, Phillipou A, Eberl C, Fantom KGM, Zappacosta F, Patel VK, Bantscheff M, Schofield CJ, Tomkinson NCO, Bush JT. Fallon DJ, et al. Among authors: bush jt. Chemistry. 2021 Dec 20;27(71):17880-17888. doi: 10.1002/chem.202102036. Epub 2021 Sep 14. Chemistry. 2021. PMID: 34328642 Free article.
Efficient Ligand Discovery Using Sulfur(VI) Fluoride Reactive Fragments.
Aatkar A, Vuorinen A, Longfield OE, Gilbert K, Peltier-Heap R, Wagner CD, Zappacosta F, Rittinger K, Chung CW, House D, Tomkinson NCO, Bush JT. Aatkar A, et al. Among authors: bush jt. ACS Chem Biol. 2023 Sep 15;18(9):1926-1937. doi: 10.1021/acschembio.3c00034. Epub 2023 Apr 21. ACS Chem Biol. 2023. PMID: 37084287 Free PMC article.
Mutate and Conjugate: A Method to Enable Rapid In-Cell Target Validation.
Thomas AM, Serafini M, Grant EK, Coombs EAJ, Bluck JP, Schiedel M, McDonough MA, Reynolds JK, Lee B, Platt M, Sharlandjieva V, Biggin PC, Duarte F, Milne TA, Bush JT, Conway SJ. Thomas AM, et al. Among authors: bush jt. ACS Chem Biol. 2023 Nov 17;18(11):2405-2417. doi: 10.1021/acschembio.3c00437. Epub 2023 Oct 24. ACS Chem Biol. 2023. PMID: 37874862 Free PMC article.
31 results