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Atazanavir, Alone or in Combination with Ritonavir, Inhibits SARS-CoV-2 Replication and Proinflammatory Cytokine Production.
Fintelman-Rodrigues N, Sacramento CQ, Ribeiro Lima C, Souza da Silva F, Ferreira AC, Mattos M, de Freitas CS, Cardoso Soares V, da Silva Gomes Dias S, Temerozo JR, Miranda MD, Matos AR, Bozza FA, Carels N, Alves CR, Siqueira MM, Bozza PT, Souza TML. Fintelman-Rodrigues N, et al. Among authors: alves cr. Antimicrob Agents Chemother. 2020 Sep 21;64(10):e00825-20. doi: 10.1128/AAC.00825-20. Print 2020 Sep 21. Antimicrob Agents Chemother. 2020. PMID: 32759267 Free PMC article.
Epoxy-α-lapachone has in vitro and in vivo anti-leishmania (Leishmania) amazonensis effects and inhibits serine proteinase activity in this parasite.
Souza-Silva F, Bourguignon SC, Pereira BA, Côrtes LM, de Oliveira LF, Henriques-Pons A, Finkelstein LC, Ferreira VF, Carneiro PF, de Pinho RT, Caffarena ER, Alves CR. Souza-Silva F, et al. Among authors: alves cr. Antimicrob Agents Chemother. 2015 Apr;59(4):1910-8. doi: 10.1128/AAC.04742-14. Epub 2015 Jan 12. Antimicrob Agents Chemother. 2015. PMID: 25583728 Free PMC article.
SARS-CoV-2 Proteins Bind to Hemoglobin and Its Metabolites.
Lechuga GC, Souza-Silva F, Sacramento CQ, Trugilho MRO, Valente RH, Napoleão-Pêgo P, Dias SSG, Fintelman-Rodrigues N, Temerozo JR, Carels N, Alves CR, Pereira MCS, Provance DW Jr, Souza TML, De-Simone SG. Lechuga GC, et al. Among authors: alves cr. Int J Mol Sci. 2021 Aug 21;22(16):9035. doi: 10.3390/ijms22169035. Int J Mol Sci. 2021. PMID: 34445741 Free PMC article.
Proteinase inhibitors: a promising drug class for treating leishmaniasis.
Pereira BA, Souza-Silva F, Silva-Almeida M, Santos-de-Souza R, Gonçalves de Oliveira LF, Ribeiro-Guimarães ML, Alves CR. Pereira BA, et al. Among authors: alves cr. Curr Drug Targets. 2014;15(12):1121-31. doi: 10.2174/1389450115666141016150007. Curr Drug Targets. 2014. PMID: 25323706 Review.
Synthesis, structure-activity relationship and trypanocidal activity of pyrazole-imidazoline and new pyrazole-tetrahydropyrimidine hybrids as promising chemotherapeutic agents for Chagas disease.
Monteiro ME, Lechuga G, Lara LS, Souto BA, Viganó MG, Bourguignon SC, Calvet CM, Oliveira FOR Jr, Alves CR, Souza-Silva F, Santos MS, Pereira MCS. Monteiro ME, et al. Among authors: alves cr. Eur J Med Chem. 2019 Nov 15;182:111610. doi: 10.1016/j.ejmech.2019.111610. Epub 2019 Aug 10. Eur J Med Chem. 2019. PMID: 31434040
Trypanosoma cruzi: insights into naphthoquinone effects on growth and proteinase activity.
Bourguignon SC, Cavalcanti DF, de Souza AM, Castro HC, Rodrigues CR, Albuquerque MG, Santos DO, da Silva GG, da Silva FC, Ferreira VF, de Pinho RT, Alves CR. Bourguignon SC, et al. Among authors: alves cr. Exp Parasitol. 2011 Jan;127(1):160-6. doi: 10.1016/j.exppara.2010.07.007. Epub 2010 Jul 18. Exp Parasitol. 2011. PMID: 20647011 Free article.
225 results