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RNAmut: robust identification of somatic mutations in acute myeloid leukemia using RNA-sequencing.
Gu M, Zwiebel M, Ong SH, Boughton N, Nomdedeu J, Basheer F, Nannya Y, Quiros PM, Ogawa S, Cazzola M, Rad R, Butler AP, Vijayabaskar MS, Vassiliou GS. Gu M, et al. Among authors: ong sh. Haematologica. 2020 Jun;105(6):e290-e293. doi: 10.3324/haematol.2019.230821. Epub 2019 Oct 24. Haematologica. 2020. PMID: 31649132 Free PMC article. No abstract available.
AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kβ/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitors.
Dunn S, Eberlein C, Yu J, Gris-Oliver A, Ong SH, Yelland U, Cureton N, Staniszewska A, McEwen R, Fox M, Pilling J, Hopcroft P, Coker EA, Jaaks P, Garnett MJ, Isherwood B, Serra V, Davies BR, Barry ST, Lynch JT, Yusa K. Dunn S, et al. Among authors: ong sh. Oncogene. 2022 Nov;41(46):5046-5060. doi: 10.1038/s41388-022-02482-9. Epub 2022 Oct 14. Oncogene. 2022. PMID: 36241868 Free PMC article.
Mutant clones in normal epithelium outcompete and eliminate emerging tumours.
Colom B, Herms A, Hall MWJ, Dentro SC, King C, Sood RK, Alcolea MP, Piedrafita G, Fernandez-Antoran D, Ong SH, Fowler JC, Mahbubani KT, Saeb-Parsy K, Gerstung M, Hall BA, Jones PH. Colom B, et al. Among authors: ong sh. Nature. 2021 Oct;598(7881):510-514. doi: 10.1038/s41586-021-03965-7. Epub 2021 Oct 13. Nature. 2021. PMID: 34646013 Free PMC article.
Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations.
Murai K, Skrupskelyte G, Piedrafita G, Hall M, Kostiou V, Ong SH, Nagy T, Cagan A, Goulding D, Klein AM, Hall BA, Jones PH. Murai K, et al. Among authors: ong sh. Cell Stem Cell. 2018 Nov 1;23(5):687-699.e8. doi: 10.1016/j.stem.2018.08.017. Epub 2018 Sep 27. Cell Stem Cell. 2018. PMID: 30269904 Free PMC article.
Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation.
Fernandez-Antoran D, Piedrafita G, Murai K, Ong SH, Herms A, Frezza C, Jones PH. Fernandez-Antoran D, et al. Among authors: ong sh. Cell Stem Cell. 2019 Sep 5;25(3):329-341.e6. doi: 10.1016/j.stem.2019.06.011. Epub 2019 Jul 18. Cell Stem Cell. 2019. PMID: 31327664 Free PMC article.
257 results