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Discovery of Marburg virus neutralizing antibodies from virus-naïve human antibody repertoires using large-scale structural predictions.
Bozhanova NG, Sangha AK, Sevy AM, Gilchuk P, Huang K, Nargi RS, Reidy JX, Trivette A, Carnahan RH, Bukreyev A, Crowe JE Jr, Meiler J. Bozhanova NG, et al. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31142-31148. doi: 10.1073/pnas.1922654117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229516 Free PMC article.
Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface.
Zost SJ, Dong J, Gilchuk IM, Gilchuk P, Thornburg NJ, Bangaru S, Kose N, Finn JA, Bombardi R, Soto C, Chen EC, Nargi RS, Sutton RE, Irving RP, Suryadevara N, Westover JB, Carnahan RH, Turner HL, Li S, Ward AB, Crowe JE Jr. Zost SJ, et al. Among authors: nargi rs. J Clin Invest. 2021 Aug 2;131(15):e146791. doi: 10.1172/JCI146791. J Clin Invest. 2021. PMID: 34156974 Free PMC article.
Human VH1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis.
Bennett MR, Dong J, Bombardi RG, Soto C, Parrington HM, Nargi RS, Schoeder CT, Nagel MB, Schey KL, Meiler J, Skaar EP, Crowe JE Jr. Bennett MR, et al. Among authors: nargi rs. mBio. 2019 Oct 22;10(5):e02473-19. doi: 10.1128/mBio.02473-19. mBio. 2019. PMID: 31641091 Free PMC article.
Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.
Gilchuk P, Murin CD, Milligan JC, Cross RW, Mire CE, Ilinykh PA, Huang K, Kuzmina N, Altman PX, Hui S, Gunn BM, Bryan AL, Davidson E, Doranz BJ, Turner HL, Alkutkar T, Flinko R, Orlandi C, Carnahan R, Nargi R, Bombardi RG, Vodzak ME, Li S, Okoli A, Ibeawuchi M, Ohiaeri B, Lewis GK, Alter G, Bukreyev A, Saphire EO, Geisbert TW, Ward AB, Crowe JE Jr. Gilchuk P, et al. Among authors: nargi r. Immunity. 2020 Feb 18;52(2):388-403.e12. doi: 10.1016/j.immuni.2020.01.001. Epub 2020 Feb 4. Immunity. 2020. PMID: 32023489 Free PMC article.
Epitope-focused immunogen design based on the ebolavirus glycoprotein HR2-MPER region.
Schoeder CT, Gilchuk P, Sangha AK, Ledwitch KV, Malherbe DC, Zhang X, Binshtein E, Williamson LE, Martina CE, Dong J, Armstrong E, Sutton R, Nargi R, Rodriguez J, Kuzmina N, Fiala B, King NP, Bukreyev A, Crowe JE Jr, Meiler J. Schoeder CT, et al. Among authors: nargi r. PLoS Pathog. 2022 May 18;18(5):e1010518. doi: 10.1371/journal.ppat.1010518. eCollection 2022 May. PLoS Pathog. 2022. PMID: 35584193 Free PMC article.
Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection.
Williamson LE, Gilliland T Jr, Yadav PK, Binshtein E, Bombardi R, Kose N, Nargi RS, Sutton RE, Durie CL, Armstrong E, Carnahan RH, Walker LM, Kim AS, Fox JM, Diamond MS, Ohi MD, Klimstra WB, Crowe JE Jr. Williamson LE, et al. Among authors: nargi rs. Cell. 2020 Dec 23;183(7):1884-1900.e23. doi: 10.1016/j.cell.2020.11.011. Epub 2020 Dec 9. Cell. 2020. PMID: 33301709 Free PMC article.
34 results