Egan DA - Search Results

1

Human placental chorionic renin: production, purification and characterization.

Egan DA, Grzegorczyk V, Tricarico KA, Rueter A, Holleman WH, Marcotte PA. Egan DA, et al. Biochim Biophys Acta. 1988 Apr 14;965(1):68-75. doi: 10.1016/0304-4165(88)90152-3. Biochim Biophys Acta. 1988. PMID: 3280035

2

Recombinant human prorenin from CHO cells: expression and purification.

Holzman TF, Chung CC, Edalji R, Egan DA, Gubbins EJ, Rueter A, Howard G, Yang LK, Pederson TM, Krafft GA, et al. Holzman TF, et al. Among authors: egan da. J Protein Chem. 1990 Dec;9(6):663-72. doi: 10.1007/BF01024761. J Protein Chem. 1990. PMID: 1963533

3

Pure human inactive renin. Evidence that native inactive renin is prorenin.

Higashimori K, Mizuno K, Nakajo S, Boehm FH, Marcotte PA, Egan DA, Holleman WH, Heusser C, Poisner AM, Inagami T. Higashimori K, et al. Among authors: egan da. J Biol Chem. 1989 Sep 5;264(25):14662-7. J Biol Chem. 1989. PMID: 2670924 Free article.

4

Design of a well-absorbed renin inhibitor.

Rosenberg SH, Kleinert HD, Stein HH, Martin DL, Chekal MA, Cohen J, Egan DA, Tricarico KA, Baker WR. Rosenberg SH, et al. Among authors: egan da. J Med Chem. 1991 Jan;34(1):469-71. doi: 10.1021/jm00105a073. J Med Chem. 1991. PMID: 1992151 No abstract available.

5

Renin inhibitors. Dipeptide analogues of angiotensinogen utilizing a dihydroxyethylene transition-state mimic at the scissile bond to impart greater inhibitory potency.

Luly JR, BaMaung N, Soderquist J, Fung AK, Stein H, Kleinert HD, Marcotte PA, Egan DA, Bopp B, Merits I, et al. Luly JR, et al. Among authors: egan da. J Med Chem. 1988 Dec;31(12):2264-76. doi: 10.1021/jm00120a005. J Med Chem. 1988. PMID: 3143009

6

Characterization of recombinant human renin: kinetics, pH-stability, and peptidomimetic inhibitor binding.

Holzman TF, Chung CC, Edalji R, Egan DA, Martin M, Gubbins EJ, Krafft GA, Wang GT, Thomas AM, Rosenberg SH, et al. Holzman TF, et al. Among authors: egan da. J Protein Chem. 1991 Oct;10(5):553-63. doi: 10.1007/BF01025483. J Protein Chem. 1991. PMID: 1799412

7

Preliminary characterization of a cloned neutral isoelectric form of the human peptidyl prolyl isomerase cyclophilin.

Holzman TF, Egan DA, Edalji R, Simmer RL, Helfrich R, Taylor A, Burres NS. Holzman TF, et al. Among authors: egan da. J Biol Chem. 1991 Feb 5;266(4):2474-9. J Biol Chem. 1991. PMID: 1989998 Free article.

8

High-level expression of recombinant human FK-binding protein from a fusion precursor.

Edalji R, Pilot-Matias TJ, Pratt SD, Egan DA, Severin JM, Gubbins EG, Petros AM, Fesik SW, Burres NS, Holzman TF. Edalji R, et al. Among authors: egan da. J Protein Chem. 1992 Jun;11(3):213-23. doi: 10.1007/BF01024859. J Protein Chem. 1992. PMID: 1382438

9

Nonpeptide renin inhibitors employing a novel 3-aza(or oxa)-2,4-dialkyl glutaric acid moiety as a P2/P3 amide bond replacement.

Baker WR, Fung AK, Kleinert HD, Stein HH, Plattner JJ, Armiger YL, Condon SL, Cohen J, Egan DA, Barlow JL, et al. Baker WR, et al. Among authors: egan da. J Med Chem. 1992 May 15;35(10):1722-34. doi: 10.1021/jm00088a006. J Med Chem. 1992. PMID: 1588554

10

C-terminal modifications of nonpeptide renin inhibitors: improved oral bioavailability via modification of physicochemical properties.

Boyd SA, Fung AK, Baker WR, Mantei RA, Armiger YL, Stein HH, Cohen J, Egan DA, Barlow JL, Klinghofer V, et al. Boyd SA, et al. Among authors: egan da. J Med Chem. 1992 May 15;35(10):1735-46. doi: 10.1021/jm00088a007. J Med Chem. 1992. PMID: 1588555

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