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Page 1
Interleukin-6 in neuromyelitis optica spectrum disorder pathophysiology.
Fujihara K, Bennett JL, de Seze J, Haramura M, Kleiter I, Weinshenker BG, Kang D, Mughal T, Yamamura T. Fujihara K, et al. Among authors: haramura m. Neurol Neuroimmunol Neuroinflamm. 2020 Aug 20;7(5):e841. doi: 10.1212/NXI.0000000000000841. Print 2020 Sep 3. Neurol Neuroimmunol Neuroinflamm. 2020. PMID: 32820020 Free PMC article. Review.
Patient-reported burden of symptoms in neuromyelitis optica: A secondary analysis on pain and quality of life.
Fujihara K, Hattori S, Kleiter I, Levy M, Matsuda Y, Mitsutake A, Haramura M, Palace J, Yamamura T; Guthy-Jackson Charitable Foundation NMOSD Quality of Life Working Group. Fujihara K, et al. Among authors: haramura m. J Neurol Sci. 2021 Sep 15;428:117546. doi: 10.1016/j.jns.2021.117546. Epub 2021 Jun 19. J Neurol Sci. 2021. PMID: 34252701 Free article.
Neuromyelitis optica spectrum disorder: Patient experience and quality of life.
Beekman J, Keisler A, Pedraza O, Haramura M, Gianella-Borradori A, Katz E, Ratchford JN, Barron G, Cook LJ, Behne JM, Blaschke TF, Smith TJ, Yeaman MR. Beekman J, et al. Among authors: haramura m. Neurol Neuroimmunol Neuroinflamm. 2019 Jun 20;6(4):e580. doi: 10.1212/NXI.0000000000000580. eCollection 2019 Jul. Neurol Neuroimmunol Neuroinflamm. 2019. PMID: 31355316 Free PMC article.
Design and synthesis of peptidomimetic factor VIIa inhibitors.
Shiraishi T, Kadono S, Haramura M, Kodama H, Ono Y, Iikura H, Esaki T, Koga T, Hattori K, Watanabe Y, Sakamoto A, Yoshihashi K, Kitazawa T, Esaki K, Ohta M, Sato H, Kozono T. Shiraishi T, et al. Among authors: haramura m. Chem Pharm Bull (Tokyo). 2010 Jan;58(1):38-44. doi: 10.1248/cpb.58.38. Chem Pharm Bull (Tokyo). 2010. PMID: 20045964 Free article.
Novel interactions of large P3 moiety and small P4 moiety in the binding of the peptide mimetic factor VIIa inhibitor.
Kadono S, Sakamoto A, Kikuchi Y, Oh-Eda M, Yabuta N, Yoshihashi K, Kitazawa T, Suzuki T, Koga T, Hattori K, Shiraishi T, Haramura M, Kodama H, Ono Y, Esaki T, Sato H, Watanabe Y, Itoh S, Ohta M, Kozono T. Kadono S, et al. Among authors: haramura m. Biochem Biophys Res Commun. 2005 Jan 28;326(4):859-65. doi: 10.1016/j.bbrc.2004.11.108. Biochem Biophys Res Commun. 2005. PMID: 15607748
Structure-based design of P3 moieties in the peptide mimetic factor VIIa inhibitor.
Kadono S, Sakamoto A, Kikuchi Y, Oh-eda M, Yabuta N, Yoshihashi K, Kitazawa T, Suzuki T, Koga T, Hattori K, Shiraishi T, Haramura M, Kodama H, Ono Y, Esaki T, Sato H, Watanabe Y, Itoh S, Ohta M, Kozono T. Kadono S, et al. Among authors: haramura m. Biochem Biophys Res Commun. 2005 Feb 11;327(2):589-96. doi: 10.1016/j.bbrc.2004.12.042. Biochem Biophys Res Commun. 2005. PMID: 15629154
Structure of human factor VIIa/tissue factor in complex with a peptide-mimetic inhibitor: high selectivity against thrombin by introducing two charged groups in P2 and P4.
Kadono S, Sakamoto A, Kikuchi Y, Oh-Eda M, Yabuta N, Koga T, Hattori K, Shiraishi T, Haramura M, Kodama H, Ono Y, Esaki T, Sato H, Watanabe Y, Itoh S, Ohta M, Kozono T. Kadono S, et al. Among authors: haramura m. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Feb 1;61(Pt 2):169-73. doi: 10.1107/S1744309105000047. Epub 2005 Jan 20. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005. PMID: 16510984 Free PMC article.
Factor VIIa inhibitors: target hopping in the serine protease family using X-ray structure determination.
Shiraishi T, Kadono S, Haramura M, Kodama H, Ono Y, Iikura H, Esaki T, Koga T, Hattori K, Watanabe Y, Sakamoto A, Yoshihashi K, Kitazawa T, Esaki K, Ohta M, Sato H, Kozono T. Shiraishi T, et al. Among authors: haramura m. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4533-7. doi: 10.1016/j.bmcl.2008.07.044. Epub 2008 Jul 16. Bioorg Med Chem Lett. 2008. PMID: 18674905
36 results