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CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice.
Mancuso R, Fryatt G, Cleal M, Obst J, Pipi E, Monzón-Sandoval J, Ribe E, Winchester L, Webber C, Nevado A, Jacobs T, Austin N, Theunis C, Grauwen K, Daniela Ruiz E, Mudher A, Vicente-Rodriguez M, Parker CA, Simmons C, Cash D, Richardson J; NIMA Consortium; Jones DNC, Lovestone S, Gómez-Nicola D, Perry VH. Mancuso R, et al. Brain. 2019 Oct 1;142(10):3243-3264. doi: 10.1093/brain/awz241. Brain. 2019. PMID: 31504240 Free PMC article.
TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages.
Hall-Roberts H, Agarwal D, Obst J, Smith TB, Monzón-Sandoval J, Di Daniel E, Webber C, James WS, Mead E, Davis JB, Cowley SA. Hall-Roberts H, et al. Among authors: monzon sandoval j. Alzheimers Res Ther. 2020 Nov 16;12(1):151. doi: 10.1186/s13195-020-00709-z. Alzheimers Res Ther. 2020. PMID: 33198789 Free PMC article.
Deep phenotyping for precision medicine in Parkinson's disease.
Schalkamp AK, Rahman N, Monzón-Sandoval J, Sandor C. Schalkamp AK, et al. Among authors: monzon sandoval j. Dis Model Mech. 2022 Jun 1;15(6):dmm049376. doi: 10.1242/dmm.049376. Epub 2022 Jun 1. Dis Model Mech. 2022. PMID: 35647913 Free PMC article.
19 results