Medler J - Search Results

1

CD40- and CD95-specific antibody single chain-Baff fusion proteins display BaffR-, TACI- and BCMA-restricted agonism.

Nelke J, Medler J, Weisenberger D, Beilhack A, Wajant H. Nelke J, et al. Among authors: medler j. MAbs. 2020 Jan-Dec;12(1):1807721. doi: 10.1080/19420862.2020.1807721. MAbs. 2020. PMID: 32840410 Free PMC article.

2

TNFRSF receptor-specific antibody fusion proteins with targeting controlled FcγR-independent agonistic activity.

Medler J, Nelke J, Weisenberger D, Steinfatt T, Rothaug M, Berr S, Hünig T, Beilhack A, Wajant H. Medler J, et al. Cell Death Dis. 2019 Mar 4;10(3):224. doi: 10.1038/s41419-019-1456-x. Cell Death Dis. 2019. PMID: 30833543 Free PMC article.

3

Tumor necrosis factor receptor-2 (TNFR2): an overview of an emerging drug target.

Medler J, Wajant H. Medler J, et al. Expert Opin Ther Targets. 2019 Apr;23(4):295-307. doi: 10.1080/14728222.2019.1586886. Epub 2019 Mar 19. Expert Opin Ther Targets. 2019. PMID: 30856027 Review.

4

Single-molecule imaging reveals the oligomeric state of functional TNFα-induced plasma membrane TNFR1 clusters in cells.

Karathanasis C, Medler J, Fricke F, Smith S, Malkusch S, Widera D, Fulda S, Wajant H, van Wijk SJL, Dikic I, Heilemann M. Karathanasis C, et al. Among authors: medler j. Sci Signal. 2020 Jan 14;13(614):eaax5647. doi: 10.1126/scisignal.aax5647. Sci Signal. 2020. PMID: 31937565

5

Quantitative single-molecule imaging of TNFR1 reveals zafirlukast as antagonist of TNFR1 clustering and TNFα-induced NF-ĸB signaling.

Weinelt N, Karathanasis C, Smith S, Medler J, Malkusch S, Fulda S, Wajant H, Heilemann M, van Wijk SJL. Weinelt N, et al. Among authors: medler j. J Leukoc Biol. 2021 Feb;109(2):363-371. doi: 10.1002/JLB.2AB0420-572RR. Epub 2020 May 13. J Leukoc Biol. 2021. PMID: 32401398

6

Analysis of FcγR-Dependent Agonism of Antibodies Specific for Receptors of the Tumor Necrosis Factor (TNF) Receptor Superfamily (TNFRSF).

Medler J, Wajant H. Medler J, et al. Methods Mol Biol. 2021;2248:81-90. doi: 10.1007/978-1-0716-1130-2_6. Methods Mol Biol. 2021. PMID: 33185869

7

Analysis of Ligand-Receptor Interactions Using Bioluminescent TNF Superfamily (TNFSF) Ligand Fusion Proteins.

Kucka K, Medler J, Wajant H. Kucka K, et al. Among authors: medler j. Methods Mol Biol. 2021;2248:185-200. doi: 10.1007/978-1-0716-1130-2_13. Methods Mol Biol. 2021. PMID: 33185876

8

Membrane lymphotoxin-α₂β is a novel tumor necrosis factor (TNF) receptor 2 (TNFR2) agonist.

Kucka K, Lang I, Zhang T, Siegmund D, Medler J, Wajant H. Kucka K, et al. Among authors: medler j. Cell Death Dis. 2021 Apr 6;12(4):360. doi: 10.1038/s41419-021-03633-8. Cell Death Dis. 2021. PMID: 33824270 Free PMC article.

9

Junctional adhesion molecule C expression specifies a CD138low/neg multiple myeloma cell population in mice and humans.

Brandl A, Solimando AG, Mokhtari Z, Tabares P, Medler J, Manz H, Da Vià MC, Croci GA, Kurzwart M, Thusek S, Schneider T, Ebert R, Jakob F, Einsele H, Beilhack A. Brandl A, et al. Among authors: medler j. Blood Adv. 2022 Apr 12;6(7):2195-2206. doi: 10.1182/bloodadvances.2021004354. Blood Adv. 2022. PMID: 34861679 Free PMC article.

10

CD40- and 41BB-specific antibody fusion proteins with PDL1 blockade-restricted agonism.

Medler J, Kucka K, Melo V, Zhang T, von Rotenhan S, Ulrich J, Bremer E, Hudecek M, Beilhack A, Wajant H. Medler J, et al. Theranostics. 2022 Jan 1;12(4):1486-1499. doi: 10.7150/thno.66119. eCollection 2022. Theranostics. 2022. PMID: 35198053 Free PMC article.

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