Sago H - Search Results

1

Impairment of spatial memory accuracy improved by Cbr1 copy number resumption and GABA_B receptor-dependent enhancement of synaptic inhibition in Down syndrome model mice.

Arima-Yoshida F, Raveau M, Shimohata A, Amano K, Fukushima A, Watanave M, Kobayashi S, Hattori S, Usui M, Sago H, Mataga N, Miyakawa T, Yamakawa K, Manabe T. Arima-Yoshida F, et al. Among authors: sago h. Sci Rep. 2020 Aug 25;10(1):14187. doi: 10.1038/s41598-020-71085-9. Sci Rep. 2020. PMID: 32843708 Free PMC article.

2

Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome.

Amano K, Sago H, Uchikawa C, Suzuki T, Kotliarova SE, Nukina N, Epstein CJ, Yamakawa K. Amano K, et al. Among authors: sago h. Hum Mol Genet. 2004 Jul 1;13(13):1333-40. doi: 10.1093/hmg/ddh154. Epub 2004 May 11. Hum Mol Genet. 2004. PMID: 15138197

3

Mitochondrial dysfunction and tau hyperphosphorylation in Ts1Cje, a mouse model for Down syndrome.

Shukkur EA, Shimohata A, Akagi T, Yu W, Yamaguchi M, Murayama M, Chui D, Takeuchi T, Amano K, Subramhanya KH, Hashikawa T, Sago H, Epstein CJ, Takashima A, Yamakawa K. Shukkur EA, et al. Among authors: sago h. Hum Mol Genet. 2006 Sep 15;15(18):2752-62. doi: 10.1093/hmg/ddl211. Epub 2006 Aug 4. Hum Mol Genet. 2006. PMID: 16891409

4

Increased lipid peroxidation in Down's syndrome mouse models.

Ishihara K, Amano K, Takaki E, Ebrahim AS, Shimohata A, Shibazaki N, Inoue I, Takaki M, Ueda Y, Sago H, Epstein CJ, Yamakawa K. Ishihara K, et al. Among authors: sago h. J Neurochem. 2009 Sep;110(6):1965-76. doi: 10.1111/j.1471-4159.2009.06294.x. Epub 2009 Jul 23. J Neurochem. 2009. PMID: 19645748 Free article.

5

Enlarged brain ventricles and impaired neurogenesis in the Ts1Cje and Ts2Cje mouse models of Down syndrome.

Ishihara K, Amano K, Takaki E, Shimohata A, Sago H, Epstein CJ, Yamakawa K. Ishihara K, et al. Among authors: sago h. Cereb Cortex. 2010 May;20(5):1131-43. doi: 10.1093/cercor/bhp176. Epub 2009 Aug 26. Cereb Cortex. 2010. PMID: 19710359

6

Comparative proteomic profiling reveals aberrant cell proliferation in the brain of embryonic Ts1Cje, a mouse model of Down syndrome.

Ishihara K, Kanai S, Sago H, Yamakawa K, Akiba S. Ishihara K, et al. Among authors: sago h. Neuroscience. 2014 Dec 5;281:1-15. doi: 10.1016/j.neuroscience.2014.09.039. Epub 2014 Sep 28. Neuroscience. 2014. PMID: 25261685

7

Brain ventriculomegaly in Down syndrome mice is caused by Pcp4 dose-dependent cilia dysfunction.

Raveau M, Nakahari T, Asada S, Ishihara K, Amano K, Shimohata A, Sago H, Yamakawa K. Raveau M, et al. Among authors: sago h. Hum Mol Genet. 2017 Mar 1;26(5):923-931. doi: 10.1093/hmg/ddx007. Hum Mol Genet. 2017. PMID: 28069794

8

Ts1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism.

Shimohata A, Ishihara K, Hattori S, Miyamoto H, Morishita H, Ornthanalai G, Raveau M, Ebrahim AS, Amano K, Yamada K, Sago H, Akiba S, Mataga N, Murphy NP, Miyakawa T, Yamakawa K. Shimohata A, et al. Among authors: sago h. Exp Neurol. 2017 Jul;293:1-12. doi: 10.1016/j.expneurol.2017.03.009. Epub 2017 Mar 20. Exp Neurol. 2017. PMID: 28336394

9

Copper accumulation in the brain causes the elevation of oxidative stress and less anxious behavior in Ts1Cje mice, a model of Down syndrome.

Ishihara K, Kawashita E, Shimizu R, Nagasawa K, Yasui H, Sago H, Yamakawa K, Akiba S. Ishihara K, et al. Among authors: sago h. Free Radic Biol Med. 2019 Apr;134:248-259. doi: 10.1016/j.freeradbiomed.2019.01.015. Epub 2019 Jan 18. Free Radic Biol Med. 2019. PMID: 30660502

10

Perturbation of the immune cells and prenatal neurogenesis by the triplication of the Erg gene in mouse models of Down syndrome.

Ishihara K, Shimizu R, Takata K, Kawashita E, Amano K, Shimohata A, Low D, Nabe T, Sago H, Alexander WS, Ginhoux F, Yamakawa K, Akiba S. Ishihara K, et al. Among authors: sago h. Brain Pathol. 2020 Jan;30(1):75-91. doi: 10.1111/bpa.12758. Epub 2019 Jul 4. Brain Pathol. 2020. PMID: 31206867 Free PMC article.

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