Liu Y - Search Results

1

Enhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry.

Guo WH, Qi X, Yu X, Liu Y, Chung CI, Bai F, Lin X, Lu D, Wang L, Chen J, Su LH, Nomie KJ, Li F, Wang MC, Shu X, Onuchic JN, Woyach JA, Wang ML, Wang J. Guo WH, et al. Among authors: liu y. Nat Commun. 2020 Aug 26;11(1):4268. doi: 10.1038/s41467-020-17997-6. Nat Commun. 2020. PMID: 32848159 Free PMC article.

2

Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma.

Zhang S, Jiang VC, Han G, Hao D, Lian J, Liu Y, Cai Q, Zhang R, McIntosh J, Wang R, Dang M, Dai E, Wang Y, Santos D, Badillo M, Leeming A, Chen Z, Hartig K, Bigcal J, Zhou J, Kanagal-Shamanna R, Ok CY, Lee H, Steiner RE, Zhang J, Song X, Nair R, Ahmed S, Rodriquez A, Thirumurthi S, Jain P, Wagner-Bartak N, Hill H, Nomie K, Flowers C, Futreal A, Wang L, Wang M. Zhang S, et al. Among authors: liu y. Nat Commun. 2021 May 17;12(1):2877. doi: 10.1038/s41467-021-22872-z. Nat Commun. 2021. PMID: 34001881 Free PMC article.

3

Targeting Bruton's tyrosine kinase for the treatment of B cell associated malignancies and autoimmune diseases: Preclinical and clinical developments of small molecule inhibitors.

Zhang Z, Zhang D, Liu Y, Yang D, Ran F, Wang ML, Zhao G. Zhang Z, et al. Among authors: liu y. Arch Pharm (Weinheim). 2018 Jul;351(7):e1700369. doi: 10.1002/ardp.201700369. Epub 2018 May 9. Arch Pharm (Weinheim). 2018. PMID: 29741794 Review.

4

Pleiotropic Action of Novel Bruton's Tyrosine Kinase Inhibitor BGB-3111 in Mantle Cell Lymphoma.

Li CJ, Jiang C, Liu Y, Bell T, Ma W, Ye Y, Huang S, Guo H, Zhang H, Wang L, Wang J, Nomie K, Zhang L, Wang M. Li CJ, et al. Among authors: liu y. Mol Cancer Ther. 2019 Feb;18(2):267-277. doi: 10.1158/1535-7163.MCT-18-0478. Epub 2018 Nov 9. Mol Cancer Ther. 2019. PMID: 30413649 Free PMC article.

5

Structural optimization elaborates novel potent Akt inhibitors with promising anticancer activity.

Liu Y, Yin Y, Zhang Z, Li CJ, Zhang H, Zhang D, Jiang C, Nomie K, Zhang L, Wang ML, Zhao G. Liu Y, et al. Eur J Med Chem. 2017 Sep 29;138:543-551. doi: 10.1016/j.ejmech.2017.06.067. Epub 2017 Jun 30. Eur J Med Chem. 2017. PMID: 28704757

6

Dual inhibition of PI3K signaling and histone deacetylation halts proliferation and induces lethality in mantle cell lymphoma.

Guo H, Zeng D, Zhang H, Bell T, Yao J, Liu Y, Huang S, Li CJ, Lorence E, Zhou S, Gong T, Jiang C, Ahmed M, Yao Y, Nomie KJ, Zhang L, Wang M. Guo H, et al. Among authors: liu y. Oncogene. 2019 Mar;38(11):1802-1814. doi: 10.1038/s41388-018-0550-3. Epub 2018 Oct 25. Oncogene. 2019. PMID: 30361685

7

The CD20-specific engineered toxin antibody MT-3724 exhibits lethal effects against mantle cell lymphoma.

Huang S, Jiang C, Zhang H, Bell T, Guo H, Liu Y, Yao Y, Zeng D, Ahmed M, Nomie K, Zhang L, Wang M. Huang S, et al. Among authors: liu y. Blood Cancer J. 2018 Mar 20;8(3):33. doi: 10.1038/s41408-018-0066-7. Blood Cancer J. 2018. PMID: 29559616 Free PMC article. No abstract available.

8

PIK-75 overcomes venetoclax resistance via blocking PI3K-AKT signaling and MCL-1 expression in mantle cell lymphoma.

Huang S, Liu Y, Chen Z, Wang M, Jiang VC. Huang S, et al. Among authors: liu y. Am J Cancer Res. 2022 Mar 15;12(3):1102-1115. eCollection 2022. Am J Cancer Res. 2022. PMID: 35411248 Free PMC article.

9

Repurposing auranofin to treat TP53-mutated or PTEN-deleted refractory B-cell lymphoma.

Wang J, Wang J, Lopez E, Guo H, Zhang H, Liu Y, Chen Z, Huang S, Zhou S, Leeming A, Zhang RJ, Jung D, Shi H, Grundman H, Doakes D, Cui K, Jiang C, Ahmed M, Nomie K, Fang B, Wang M, Yao Y, Zhang L. Wang J, et al. Among authors: liu y. Blood Cancer J. 2019 Nov 28;9(12):95. doi: 10.1038/s41408-019-0259-8. Blood Cancer J. 2019. PMID: 31780660 Free PMC article. No abstract available.

10

Dual targeting of PI3K and BCL-2 overcomes ibrutinib resistance in aggressive mantle cell lymphoma.

Ye H, Huang S, Liu Y, Chen Z, Wang M, Jiang VC. Ye H, et al. Among authors: liu y. J Cell Mol Med. 2022 May;26(10):3068-3073. doi: 10.1111/jcmm.17297. Epub 2022 Mar 30. J Cell Mol Med. 2022. PMID: 35352453 Free PMC article.

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