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The T-type calcium channel isoform Cav3.1 is a target for the hypnotic effect of the anaesthetic neurosteroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile.
Timic Stamenic T, Feseha S, Manzella FM, Wallace D, Wilkey D, Corrigan T, Fiedler H, Doerr P, Krishnan K, Raol YH, Covey DF, Jevtovic-Todorovic V, Todorovic SM. Timic Stamenic T, et al. Among authors: wilkey d. Br J Anaesth. 2021 Jan;126(1):245-255. doi: 10.1016/j.bja.2020.07.022. Epub 2020 Aug 25. Br J Anaesth. 2021. PMID: 32859366 Free PMC article.
Sex-specific hypnotic effects of the neuroactive steroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile are mediated by peripheral metabolism into an active hypnotic steroid.
Manzella FM, Cabrera OH, Wilkey D, Fine-Raquet B, Klawitter J, Krishnan K, Covey DF, Jevtovic-Todorovic V, Todorovic SM. Manzella FM, et al. Among authors: wilkey d. Br J Anaesth. 2023 Feb;130(2):154-164. doi: 10.1016/j.bja.2022.09.025. Epub 2022 Nov 22. Br J Anaesth. 2023. PMID: 36428160 Free PMC article.
A plasma peptidomic signature reveals extracellular matrix remodeling and predicts prognosis in alcohol-associated hepatitis.
Sayed K, Dolin CE, Wilkey DW, Li J, Sato T, Beier JI, Argemi J, Vatsalya V, McClain CJ, Bataller R, Wahed AS, Merchant ML, Benos PV, Arteel GE. Sayed K, et al. Among authors: wilkey dw. Hepatol Commun. 2024 Jul 31;8(8):e0510. doi: 10.1097/HC9.0000000000000510. eCollection 2024 Aug 1. Hepatol Commun. 2024. PMID: 39082970 Free article.
A plasma peptidomic signature reveals extracellular matrix remodeling and predicts prognosis in alcohol-related hepatitis.
Sayed K, Dolin CE, Wilkey DW, Li J, Sato T, Beier JI, Argemi J, Bataller R, Wahed AS, Merchant ML, Benos PV, Arteel GE. Sayed K, et al. Among authors: wilkey dw. medRxiv [Preprint]. 2023 Dec 14:2023.12.13.23299905. doi: 10.1101/2023.12.13.23299905. medRxiv. 2023. Update in: Hepatol Commun. 2024 Jul 31;8(8):e0510. doi: 10.1097/HC9.0000000000000510 PMID: 38168372 Free PMC article. Updated. Preprint.
Increased expression of phosphodiesterase 4 in activated hepatic stellate cells promotes cytoskeleton remodeling and cell migration.
Elnagdy M, Wang Y, Rodriguez W, Zhang J, Bauer P, Wilkey DW, Merchant M, Pan J, Farooqui Z, Cannon R, Rai S, Maldonado C, Barve S, McClain CJ, Gobejishvili L. Elnagdy M, et al. Among authors: wilkey dw. J Pathol. 2023 Nov;261(3):361-371. doi: 10.1002/path.6194. Epub 2023 Sep 21. J Pathol. 2023. PMID: 37735782 Free PMC article.
The plasma degradome reflects later development of NASH fibrosis after liver transplant.
Li J, Sato T, Hernández-Tejero M, Beier JI, Sayed K, Benos PV, Wilkey DW, Humar A, Merchant ML, Duarte-Rojo A, Arteel GE. Li J, et al. Among authors: wilkey dw. bioRxiv [Preprint]. 2023 Feb 1:2023.01.30.526241. doi: 10.1101/2023.01.30.526241. bioRxiv. 2023. Update in: Sci Rep. 2023 Jun 20;13(1):9965. doi: 10.1038/s41598-023-36867-x PMID: 36778394 Free PMC article. Updated. Preprint.
Fibrosis resolution in the mouse liver: Role of Mmp12 and potential role of calpain 1/2.
Sato T, Head KZ, Li J, Dolin CE, Wilkey D, Skirtich N, Smith K, McCreary DD, Liu S, Beier JI, Singhi AD, McEnaney RM, Merchant ML, Arteel GE. Sato T, et al. Among authors: wilkey d. Matrix Biol Plus. 2022 Dec 28;17:100127. doi: 10.1016/j.mbplus.2022.100127. eCollection 2023 Feb. Matrix Biol Plus. 2022. PMID: 36632559 Free PMC article.
58 results