Zhang H - Search Results

1

Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans: major enzymes and transporters identified.

Pan LL, Yang Y, Hui M, Wang S, Li CY, Zhang H, Ding YH, Fu L, Diao XX, Zhong DF. Pan LL, et al. Among authors: zhang h. Acta Pharmacol Sin. 2021 Feb;42(2):311-322. doi: 10.1038/s41401-020-0481-8. Epub 2020 Aug 28. Acta Pharmacol Sin. 2021. PMID: 32860005 Free PMC article. Clinical Trial.

2

Pharmacokinetics, Safety, and Tolerability of Intravenous Felbinac Trometamol in Healthy Chinese Volunteers: A First-in-Human Single- and Multiple-Dose Escalation Phase I Study with a Randomized, Double-Blind, Placebo-Controlled Design.

Wu M, Li C, Zhang H, Sun J, Zhu X, Li X, Gao X, Wang W, Ding Y. Wu M, et al. Among authors: zhang h. CNS Drugs. 2020 Aug;34(8):867-877. doi: 10.1007/s40263-020-00739-z. CNS Drugs. 2020. PMID: 32700191 Clinical Trial.

3

A Phase I Study on the Pharmacokinetics and Pharmacodynamics of DJT1116PG, a Novel Selective Inhibitor of Sodium-glucose Cotransporter Type 2, in Healthy Individuals at Steady State.

Zhang H, Liu J, Zhu X, Li X, Chen H, Wu M, Li C, Ding Y. Zhang H, et al. Clin Ther. 2020 May;42(5):892-905.e3. doi: 10.1016/j.clinthera.2020.03.007. Epub 2020 Apr 4. Clin Ther. 2020. PMID: 32265061 Clinical Trial.

4

Safety, pharmacokinetics and pharmacodynamics of TQ-A3334, an oral toll-like receptor 7 agonist in healthy individuals.

Hu Y, Zhang H, Wu M, Liu J, Li X, Zhu X, Li C, Chen H, Liu C, Niu J, Ding Y. Hu Y, et al. Among authors: zhang h. Expert Opin Investig Drugs. 2021 Mar;30(3):263-269. doi: 10.1080/13543784.2021.1873275. Epub 2021 Jan 13. Expert Opin Investig Drugs. 2021. PMID: 33405993 Clinical Trial.

5

Pharmacokinetics and pharmacodynamics of MT-1207, a novel multitarget blocker of α1 receptor, 5-HT2A receptor, and calcium channel, in healthy subjects.

Zhang H, Wu M, Hu Y, Li C, Zheng W, Liu J, Li X, Zhu X, Ding Y. Zhang H, et al. Expert Opin Investig Drugs. 2021 Mar;30(3):271-278. doi: 10.1080/13543784.2021.1887137. Epub 2021 Mar 3. Expert Opin Investig Drugs. 2021. PMID: 33560891 Clinical Trial.

6

Safety, Pharmacokinetics, and Pharmacodynamics of a Dipeptidyl Peptidase-4 Inhibitor: A Randomized, Double-Blinded, Placebo-Controlled Daily Administration of Fotagliptin Benzoate for 14 Days for Type 2 Diabetes Mellitus.

Wu M, Li QQ, Zhang H, Zhu XX, Li XJ, Li Y, Sun HG, Ding YH. Wu M, et al. Among authors: zhang h. Clin Pharmacol Drug Dev. 2021 Jun;10(6):660-668. doi: 10.1002/cpdd.895. Epub 2021 Jan 13. Clin Pharmacol Drug Dev. 2021. PMID: 33440080 Clinical Trial.

7

Effect of moderate activity on liver function and serum lipid level in healthy subjects during the phase I clinical trial.

Zhang H, Liu T, Li C, Li X, Ding Y. Zhang H, et al. Expert Opin Drug Metab Toxicol. 2020 Dec;16(12):1217-1221. doi: 10.1080/17425255.2020.1823369. Epub 2020 Sep 23. Expert Opin Drug Metab Toxicol. 2020. PMID: 32915093

8

Safety and pharmacokinetics of a biosimilar of denosumab (KN012): Phase 1 and bioequivalence study in healthy Chinese subjects.

Zhang H, Li C, Liu J, Wu M, Li X, Zhu X, Li Q, Wang B, Mao Y, Ding Y, Jin Q. Zhang H, et al. Expert Opin Investig Drugs. 2021 Feb;30(2):185-192. doi: 10.1080/13543784.2021.1863371. Epub 2020 Dec 22. Expert Opin Investig Drugs. 2021. PMID: 33306418 Clinical Trial.

9

Safety and pharmacokinetics of a new biosimilar trastuzumab (HL02): a Phase I bioequivalence study in healthy Chinese men.

Zhang H, Liu T, Wu M, Wei H, Li C, Li X, Liu J, Chen H, Ding Y, Liu L. Zhang H, et al. Expert Opin Biol Ther. 2022 Feb;22(2):179-186. doi: 10.1080/14712598.2021.1894121. Epub 2021 Mar 17. Expert Opin Biol Ther. 2022. PMID: 33616478 Clinical Trial.

10

Tolerability, pharmacokinetics and antiviral activity of rHSA/IFNα2a for the treatment of chronic hepatitis B infection.

Ding Y, Lou J, Chen H, Li X, Wu M, Li C, Liu J, Liu C, Li Q, Zhang H, Niu J. Ding Y, et al. Among authors: zhang h. Br J Clin Pharmacol. 2017 May;83(5):1056-1071. doi: 10.1111/bcp.13184. Epub 2016 Dec 20. Br J Clin Pharmacol. 2017. PMID: 27862178 Free PMC article. Clinical Trial.

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