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Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo.
Maldini CR, Claiborne DT, Okawa K, Chen T, Dopkin DL, Shan X, Power KA, Trifonova RT, Krupp K, Phelps M, Vrbanac VD, Tanno S, Bateson T, Leslie GJ, Hoxie JA, Boutwell CL, Riley JL, Allen TM. Maldini CR, et al. Among authors: chen t. Nat Med. 2020 Nov;26(11):1776-1787. doi: 10.1038/s41591-020-1039-5. Epub 2020 Aug 31. Nat Med. 2020. PMID: 32868878 Free PMC article.
Expansion of CD25+ Innate Lymphoid Cells Reduces Atherosclerosis.
Engelbertsen D, Foks AC, Alberts-Grill N, Kuperwaser F, Chen T, Lederer JA, Jarolim P, Grabie N, Lichtman AH. Engelbertsen D, et al. Among authors: chen t. Arterioscler Thromb Vasc Biol. 2015 Dec;35(12):2526-35. doi: 10.1161/ATVBAHA.115.306048. Epub 2015 Oct 22. Arterioscler Thromb Vasc Biol. 2015. PMID: 26494229 Free PMC article.
Bioengineered omental transplant site promotes pancreatic islet allografts survival in non-human primates.
Deng H, Zhang A, Pang DRR, Xi Y, Yang Z, Matheson R, Li G, Luo H, Lee KM, Fu Q, Zou Z, Chen T, Wang Z, Rosales IA, Peters CW, Yang J, Coronel MM, Yolcu ES, Shirwan H, García AJ, Markmann JF, Lei J. Deng H, et al. Among authors: chen t. Cell Rep Med. 2023 Mar 21;4(3):100959. doi: 10.1016/j.xcrm.2023.100959. Epub 2023 Mar 1. Cell Rep Med. 2023. PMID: 36863336 Free PMC article.
GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis.
Yu H, Rimbert A, Palmer AE, Toyohara T, Xia Y, Xia F, Ferreira LMR, Chen Z, Chen T, Loaiza N, Horwitz NB, Kacergis MC, Zhao L; BIOS Consortium; Soukas AA, Kuivenhoven JA, Kathiresan S, Cowan CA. Yu H, et al. Among authors: chen z, chen t. Cell. 2019 Nov 27;179(6):1276-1288.e14. doi: 10.1016/j.cell.2019.10.034. Cell. 2019. PMID: 31778654 Free PMC article.
FasL microgels induce immune acceptance of islet allografts in nonhuman primates.
Lei J, Coronel MM, Yolcu ES, Deng H, Grimany-Nuno O, Hunckler MD, Ulker V, Yang Z, Lee KM, Zhang A, Luo H, Peters CW, Zou Z, Chen T, Wang Z, McCoy CS, Rosales IA, Markmann JF, Shirwan H, García AJ. Lei J, et al. Among authors: chen t. Sci Adv. 2022 May 13;8(19):eabm9881. doi: 10.1126/sciadv.abm9881. Epub 2022 May 13. Sci Adv. 2022. PMID: 35559682 Free PMC article.
A novel mycobacterial Hsp70-containing fusion protein targeting mesothelin augments antitumor immunity and prolongs survival in murine models of ovarian cancer and mesothelioma.
Yuan J, Kashiwagi S, Reeves P, Nezivar J, Yang Y, Arrifin NH, Nguyen M, Jean-Mary G, Tong X, Uppal P, Korochkina S, Forbes B, Chen T, Righi E, Bronson R, Chen H, Orsulic S, Brauns T, Leblanc P, Scholler N, Dranoff G, Gelfand J, Poznansky MC. Yuan J, et al. Among authors: chen t, chen h. J Hematol Oncol. 2014 Feb 24;7:15. doi: 10.1186/1756-8722-7-15. J Hematol Oncol. 2014. PMID: 24565018 Free PMC article.
Alginate encapsulant incorporating CXCL12 supports long-term allo- and xenoislet transplantation without systemic immune suppression.
Chen T, Yuan J, Duncanson S, Hibert ML, Kodish BC, Mylavaganam G, Maker M, Li H, Sremac M, Santosuosso M, Forbes B, Kashiwagi S, Cao J, Lei J, Thomas M, Hartono C, Sachs D, Markmann J, Sambanis A, Poznansky MC. Chen T, et al. Am J Transplant. 2015 Mar;15(3):618-27. doi: 10.1111/ajt.13049. Am J Transplant. 2015. PMID: 25693473 Free article.
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