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Combining STING-based neoantigen-targeted vaccine with checkpoint modulators enhances antitumor immunity in murine pancreatic cancer.
Kinkead HL, Hopkins A, Lutz E, Wu AA, Yarchoan M, Cruz K, Woolman S, Vithayathil T, Glickman LH, Ndubaku CO, McWhirter SM, Dubensky TW Jr, Armstrong TD, Jaffee EM, Zaidi N. Kinkead HL, et al. Among authors: zaidi n. JCI Insight. 2018 Oct 18;3(20):e122857. doi: 10.1172/jci.insight.122857. JCI Insight. 2018. PMID: 30333318 Free PMC article.
Immunotherapy transforms cancer treatment.
Zaidi N, Jaffee EM. Zaidi N, et al. J Clin Invest. 2019 Jan 2;129(1):46-47. doi: 10.1172/JCI126046. Epub 2018 Dec 3. J Clin Invest. 2019. PMID: 30507614 Free PMC article. No abstract available.
PD-L1 expression and tumor mutational burden are independent biomarkers in most cancers.
Yarchoan M, Albacker LA, Hopkins AC, Montesion M, Murugesan K, Vithayathil TT, Zaidi N, Azad NS, Laheru DA, Frampton GM, Jaffee EM. Yarchoan M, et al. Among authors: zaidi n. JCI Insight. 2019 Mar 21;4(6):e126908. doi: 10.1172/jci.insight.126908. eCollection 2019 Mar 21. JCI Insight. 2019. PMID: 30895946 Free PMC article.
Peptide-TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens.
Lynn GM, Sedlik C, Baharom F, Zhu Y, Ramirez-Valdez RA, Coble VL, Tobin K, Nichols SR, Itzkowitz Y, Zaidi N, Gammon JM, Blobel NJ, Denizeau J, de la Rochere P, Francica BJ, Decker B, Maciejewski M, Cheung J, Yamane H, Smelkinson MG, Francica JR, Laga R, Bernstock JD, Seymour LW, Drake CG, Jewell CM, Lantz O, Piaggio E, Ishizuka AS, Seder RA. Lynn GM, et al. Among authors: zaidi n. Nat Biotechnol. 2020 Mar;38(3):320-332. doi: 10.1038/s41587-019-0390-x. Epub 2020 Jan 13. Nat Biotechnol. 2020. PMID: 31932728 Free PMC article.
Effects of B cell-activating factor on tumor immunity.
Yarchoan M, Ho WJ, Mohan A, Shah Y, Vithayathil T, Leatherman J, Dennison L, Zaidi N, Ganguly S, Woolman S, Cruz K, Armstrong TD, Jaffee EM. Yarchoan M, et al. Among authors: zaidi n. JCI Insight. 2020 May 21;5(10):e136417. doi: 10.1172/jci.insight.136417. JCI Insight. 2020. PMID: 32434989 Free PMC article.
Multi-omic profiling of lung and liver tumor microenvironments of metastatic pancreatic cancer reveals site-specific immune regulatory pathways.
Ho WJ, Erbe R, Danilova L, Phyo Z, Bigelow E, Stein-O'Brien G, Thomas DL 2nd, Charmsaz S, Gross N, Woolman S, Cruz K, Munday RM, Zaidi N, Armstrong TD, Sztein MB, Yarchoan M, Thompson ED, Jaffee EM, Fertig EJ. Ho WJ, et al. Among authors: zaidi n. Genome Biol. 2021 May 13;22(1):154. doi: 10.1186/s13059-021-02363-6. Genome Biol. 2021. PMID: 33985562 Free PMC article.
333 results