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CAR-T cells derived from multiple myeloma patients at diagnosis have improved cytotoxic functions compared to those produced at relapse or following daratumumab treatment.
Abecassis A, Roders N, Fayon M, Choisy C, Nelson E, Harel S, Royer B, Villesuzanne C, Talbot A, Garrick D, Goodhardt M, Fermand JP, Burbridge M, Arnulf B, Bories JC. Abecassis A, et al. Among authors: goodhardt m. EJHaem. 2022 Jun 21;3(3):970-974. doi: 10.1002/jha2.479. eCollection 2022 Aug. EJHaem. 2022. PMID: 36051036 Free PMC article.
Age-Associated Decrease of the Histone Methyltransferase SUV39H1 in HSC Perturbs Heterochromatin and B Lymphoid Differentiation.
Djeghloul D, Kuranda K, Kuzniak I, Barbieri D, Naguibneva I, Choisy C, Bories JC, Dosquet C, Pla M, Vanneaux V, Socié G, Porteu F, Garrick D, Goodhardt M. Djeghloul D, et al. Among authors: goodhardt m. Stem Cell Reports. 2016 Jun 14;6(6):970-984. doi: 10.1016/j.stemcr.2016.05.007. Stem Cell Reports. 2016. PMID: 27304919 Free PMC article.
Reduced RNA turnover as a driver of cellular senescence.
Mullani N, Porozhan Y, Mangelinck A, Rachez C, Costallat M, Batsché E, Goodhardt M, Cenci G, Mann C, Muchardt C. Mullani N, et al. Among authors: goodhardt m. Life Sci Alliance. 2021 Jan 14;4(3):e202000809. doi: 10.26508/lsa.202000809. Print 2021 Mar. Life Sci Alliance. 2021. PMID: 33446491 Free PMC article.
AF1q/MLLT11 regulates the emergence of human prothymocytes through cooperative interaction with the Notch signaling pathway.
Parcelier A, Maharzi N, Delord M, Robledo-Sarmiento M, Nelson E, Belakhdar-Mekid H, Pla M, Kuranda K, Parietti V, Goodhardt M, Legrand N, Bernstein ID, Gluckman JC, Sigaux F, Canque B. Parcelier A, et al. Among authors: goodhardt m. Blood. 2011 Aug 18;118(7):1784-96. doi: 10.1182/blood-2011-01-333179. Epub 2011 Jun 28. Blood. 2011. PMID: 21715312 Free PMC article.
54 results