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Page 1
Local intracerebral inhibition of IRE1 by MKC8866 sensitizes glioblastoma to irradiation/chemotherapy in vivo.
Le Reste PJ, Pineau R, Voutetakis K, Samal J, Jégou G, Lhomond S, Gorman AM, Samali A, Patterson JB, Zeng Q, Pandit A, Aubry M, Soriano N, Etcheverry A, Chatziioannou A, Mosser J, Avril T, Chevet E. Le Reste PJ, et al. Among authors: chatziioannou a. Cancer Lett. 2020 Dec 1;494:73-83. doi: 10.1016/j.canlet.2020.08.028. Epub 2020 Sep 1. Cancer Lett. 2020. PMID: 32882336
Dual IRE1 RNase functions dictate glioblastoma development.
Lhomond S, Avril T, Dejeans N, Voutetakis K, Doultsinos D, McMahon M, Pineau R, Obacz J, Papadodima O, Jouan F, Bourien H, Logotheti M, Jégou G, Pallares-Lupon N, Schmit K, Le Reste PJ, Etcheverry A, Mosser J, Barroso K, Vauléon E, Maurel M, Samali A, Patterson JB, Pluquet O, Hetz C, Quillien V, Chatziioannou A, Chevet E. Lhomond S, et al. Among authors: chatziioannou a. EMBO Mol Med. 2018 Mar;10(3):e7929. doi: 10.15252/emmm.201707929. EMBO Mol Med. 2018. PMID: 29311133 Free PMC article.
Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance.
Rubio-Patiño C, Bossowski JP, De Donatis GM, Mondragón L, Villa E, Aira LE, Chiche J, Mhaidly R, Lebeaupin C, Marchetti S, Voutetakis K, Chatziioannou A, Castelli FA, Lamourette P, Chu-Van E, Fenaille F, Avril T, Passeron T, Patterson JB, Verhoeyen E, Bailly-Maitre B, Chevet E, Ricci JE. Rubio-Patiño C, et al. Among authors: chatziioannou a. Cell Metab. 2018 Apr 3;27(4):828-842.e7. doi: 10.1016/j.cmet.2018.02.009. Cell Metab. 2018. PMID: 29551590 Free article.
Transcription of the NKG2D ligand MICA is suppressed by the IRE1/XBP1 pathway of the unfolded protein response through the regulation of E2F1.
Obiedat A, Seidel E, Mahameed M, Berhani O, Tsukerman P, Voutetakis K, Chatziioannou A, McMahon M, Avril T, Chevet E, Mandelboim O, Tirosh B. Obiedat A, et al. Among authors: chatziioannou a. FASEB J. 2019 Mar;33(3):3481-3495. doi: 10.1096/fj.201801350RR. Epub 2018 Nov 19. FASEB J. 2019. PMID: 30452881
While mechanisms that connect XBP1 to E2F1 are not fully understood, we implicate a few microRNA molecules that are modulated by ER stress and possess dual suppression of E2F1 and MICA. Because of the importance of E2F1 and MICA in cancer progression and recognition, these …
While mechanisms that connect XBP1 to E2F1 are not fully understood, we implicate a few microRNA molecules that are modulated by ER s …
Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation.
Maurel M, Obacz J, Avril T, Ding YP, Papadodima O, Treton X, Daniel F, Pilalis E, Hörberg J, Hou W, Beauchamp MC, Tourneur-Marsille J, Cazals-Hatem D, Sommerova L, Samali A, Tavernier J, Hrstka R, Dupont A, Fessart D, Delom F, Fernandez-Zapico ME, Jansen G, Eriksson LA, Thomas DY, Jerome-Majewska L, Hupp T, Chatziioannou A, Chevet E, Ogier-Denis E. Maurel M, et al. Among authors: chatziioannou a. EMBO Mol Med. 2019 Jun;11(6):e10120. doi: 10.15252/emmm.201810120. EMBO Mol Med. 2019. PMID: 31040128 Free PMC article.
CD90/Thy-1, a Cancer-Associated Cell Surface Signaling Molecule.
Sauzay C, Voutetakis K, Chatziioannou A, Chevet E, Avril T. Sauzay C, et al. Among authors: chatziioannou a. Front Cell Dev Biol. 2019 Apr 26;7:66. doi: 10.3389/fcell.2019.00066. eCollection 2019. Front Cell Dev Biol. 2019. PMID: 31080802 Free PMC article. Review.
The Expression of Myeloproliferative Neoplasm-Associated Calreticulin Variants Depends on the Functionality of ER-Associated Degradation.
Mansier O, Prouzet-Mauléon V, Jégou G, Barroso K, Raymundo DP, Chauveau A, Dumas PY, Lagarde V, Turcq B, Pasquet JM, Viallard JF, James C, Praloran V, Voutetakis K, Chatziioannou A, Mahon FX, Chevet E, Lippert E. Mansier O, et al. Among authors: chatziioannou a. Cancers (Basel). 2019 Dec 2;11(12):1921. doi: 10.3390/cancers11121921. Cancers (Basel). 2019. PMID: 31810292 Free PMC article.
Role of the early secretory pathway in SARS-CoV-2 infection.
Sicari D, Chatziioannou A, Koutsandreas T, Sitia R, Chevet E. Sicari D, et al. Among authors: chatziioannou a. J Cell Biol. 2020 Sep 7;219(9):e202006005. doi: 10.1083/jcb.202006005. J Cell Biol. 2020. PMID: 32725137 Free PMC article. Review.
305 results