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1D Genome Sequencing on the Oxford Nanopore MinION.
Goodwin S, Wappel R, McCombie WR. Goodwin S, et al. Among authors: wappel r. Curr Protoc Hum Genet. 2017 Jul 11;94:18.11.1-18.11.14. doi: 10.1002/cphg.39. Curr Protoc Hum Genet. 2017. PMID: 28696556
Direct sequencing of insect symbionts via nanopore adaptive sampling.
Badger JH, Giordano R, Zimin A, Wappel R, Eskipehlivan SM, Muller S, Donthu R, Soto-Adames F, Vieira P, Zasada I, Goodwin S. Badger JH, et al. Among authors: wappel r. Curr Opin Insect Sci. 2024 Feb;61:101135. doi: 10.1016/j.cois.2023.101135. Epub 2023 Nov 4. Curr Opin Insect Sci. 2024. PMID: 37926187 Review.
Mapping medically relevant RNA isoform diversity in the aged human frontal cortex with deep long-read RNA-seq.
Aguzzoli Heberle B, Brandon JA, Page ML, Nations KA, Dikobe KI, White BJ, Gordon LA, Fox GA, Wadsworth ME, Doyle PH, Williams BA, Fox EJ, Shantaraman A, Ryten M, Goodwin S, Ghiban E, Wappel R, Mavruk-Eskipehlivan S, Miller JB, Seyfried NT, Nelson PT, Fryer JD, Ebbert MTW. Aguzzoli Heberle B, et al. Among authors: wappel r. Nat Biotechnol. 2024 May 22. doi: 10.1038/s41587-024-02245-9. Online ahead of print. Nat Biotechnol. 2024. PMID: 38778214
Using deep long-read RNAseq in Alzheimer's disease brain to assess medical relevance of RNA isoform diversity.
Heberle BA, Brandon JA, Page ML, Nations KA, Dikobe KI, White BJ, Gordon LA, Fox GA, Wadsworth ME, Doyle PH, Williams BA, Fox EJ, Shantaraman A, Ryten M, Goodwin S, Ghiban E, Wappel R, Mavruk-Eskipehlivan S, Miller JB, Seyfried NT, Nelson PT, Fryer JD, Ebbert MTW. Heberle BA, et al. Among authors: wappel r. bioRxiv [Preprint]. 2023 Dec 11:2023.08.06.552162. doi: 10.1101/2023.08.06.552162. bioRxiv. 2023. Update in: Nat Biotechnol. 2024 May 22. doi: 10.1038/s41587-024-02245-9 PMID: 37609156 Free PMC article. Updated. Preprint.