Pan C - Search Results

1

Engineered Fc-glycosylation switch to eliminate antibody effector function.

Zhou Q, Jaworski J, Zhou Y, Valente D, Cotton J, Honey D, Boudanova E, Beninga J, Rao E, Wei R, Mauriac C, Pan C, Park A, Qiu H. Zhou Q, et al. Among authors: pan c. MAbs. 2020 Jan-Dec;12(1):1814583. doi: 10.1080/19420862.2020.1814583. MAbs. 2020. PMID: 32892677 Free PMC article.

2

Engineering an anti-CD52 antibody for enhanced deamidation stability.

Qiu H, Wei R, Jaworski J, Boudanova E, Hughes H, VanPatten S, Lund A, Day J, Zhou Y, McSherry T, Pan CQ, Sendak R. Qiu H, et al. MAbs. 2019 Oct;11(7):1266-1275. doi: 10.1080/19420862.2019.1631117. Epub 2019 Jul 18. MAbs. 2019. PMID: 31199181 Free PMC article.

3

Impact of cysteine variants on the structure, activity, and stability of recombinant human α-galactosidase A.

Qiu H, Honey DM, Kingsbury JS, Park A, Boudanova E, Wei RR, Pan CQ, Edmunds T. Qiu H, et al. Protein Sci. 2015 Sep;24(9):1401-11. doi: 10.1002/pro.2719. Epub 2015 Jul 14. Protein Sci. 2015. PMID: 26044846 Free PMC article.

4

Site-specific PEGylation of human thyroid stimulating hormone to prolong duration of action.

Qiu H, Boudanova E, Park A, Bird JJ, Honey DM, Zarazinski C, Greene B, Kingsbury JS, Boucher S, Pollock J, McPherson JM, Pan CQ. Qiu H, et al. Among authors: pan cq. Bioconjug Chem. 2013 Mar 20;24(3):408-18. doi: 10.1021/bc300519h. Epub 2013 Feb 11. Bioconjug Chem. 2013. PMID: 23350694

5

Development of a simple and rapid method for producing non-fucosylated oligomannose containing antibodies with increased effector function.

Zhou Q, Shankara S, Roy A, Qiu H, Estes S, McVie-Wylie A, Culm-Merdek K, Park A, Pan C, Edmunds T. Zhou Q, et al. Among authors: pan c. Biotechnol Bioeng. 2008 Feb 15;99(3):652-65. doi: 10.1002/bit.21598. Biotechnol Bioeng. 2008. PMID: 17680659

6

In vitro and in vivo evaluation of a non-carbohydrate targeting platform for lysosomal proteins.

Stefano JE, Hou L, Honey D, Kyazike J, Park A, Zhou Q, Pan CQ, Edmunds T. Stefano JE, et al. J Control Release. 2009 Apr 17;135(2):113-8. doi: 10.1016/j.jconrel.2008.12.006. Epub 2008 Dec 24. J Control Release. 2009. PMID: 19146893

7

High-affinity VEGF antagonists by oligomerization of a minimal sequence VEGF-binding domain.

Stefano JE, Bird J, Kyazike J, Cheng AW, Boudanova E, Dwyer M, Hou L, Qiu H, Matthews G, O'Callaghan M, Pan CQ. Stefano JE, et al. Bioconjug Chem. 2012 Dec 19;23(12):2354-64. doi: 10.1021/bc300301m. Epub 2012 Dec 10. Bioconjug Chem. 2012. PMID: 23176598

8

Carbohydrate-mediated polyethylene glycol conjugation of TSH improves its pharmacological properties.

Park A, Honey DM, Hou L, Bird JJ, Zarazinski C, Searles M, Braithwaite C, Kingsbury JS, Kyazike J, Culm-Merdek K, Greene B, Stefano JE, Qiu H, McPherson JM, Pan CQ. Park A, et al. Among authors: pan cq. Endocrinology. 2013 Mar;154(3):1373-83. doi: 10.1210/en.2012-2010. Epub 2013 Feb 6. Endocrinology. 2013. PMID: 23389953

9

Structures of a pan-specific antagonist antibody complexed to different isoforms of TGFβ reveal structural plasticity of antibody-antigen interactions.

Moulin A, Mathieu M, Lawrence C, Bigelow R, Levine M, Hamel C, Marquette JP, Le Parc J, Loux C, Ferrari P, Capdevila C, Dumas J, Dumas B, Rak A, Bird J, Qiu H, Pan CQ, Edmunds T, Wei RR. Moulin A, et al. Among authors: pan cq. Protein Sci. 2014 Dec;23(12):1698-707. doi: 10.1002/pro.2548. Epub 2014 Sep 26. Protein Sci. 2014. PMID: 25209176 Free PMC article.

10

Site-specific antibody-drug conjugation through glycoengineering.

Zhou Q, Stefano JE, Manning C, Kyazike J, Chen B, Gianolio DA, Park A, Busch M, Bird J, Zheng X, Simonds-Mannes H, Kim J, Gregory RC, Miller RJ, Brondyk WH, Dhal PK, Pan CQ. Zhou Q, et al. Among authors: pan cq. Bioconjug Chem. 2014 Mar 19;25(3):510-20. doi: 10.1021/bc400505q. Epub 2014 Feb 28. Bioconjug Chem. 2014. PMID: 24533768

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