Zhou Q - Search Results

1

Engineered Fc-glycosylation switch to eliminate antibody effector function.

Zhou Q, Jaworski J, Zhou Y, Valente D, Cotton J, Honey D, Boudanova E, Beninga J, Rao E, Wei R, Mauriac C, Pan C, Park A, Qiu H. Zhou Q, et al. Among authors: zhou y. MAbs. 2020 Jan-Dec;12(1):1814583. doi: 10.1080/19420862.2020.1814583. MAbs. 2020. PMID: 32892677 Free PMC article.

2

Development of a simple and rapid method for producing non-fucosylated oligomannose containing antibodies with increased effector function.

Zhou Q, Shankara S, Roy A, Qiu H, Estes S, McVie-Wylie A, Culm-Merdek K, Park A, Pan C, Edmunds T. Zhou Q, et al. Biotechnol Bioeng. 2008 Feb 15;99(3):652-65. doi: 10.1002/bit.21598. Biotechnol Bioeng. 2008. PMID: 17680659

3

In vitro and in vivo evaluation of a non-carbohydrate targeting platform for lysosomal proteins.

Stefano JE, Hou L, Honey D, Kyazike J, Park A, Zhou Q, Pan CQ, Edmunds T. Stefano JE, et al. Among authors: zhou q. J Control Release. 2009 Apr 17;135(2):113-8. doi: 10.1016/j.jconrel.2008.12.006. Epub 2008 Dec 24. J Control Release. 2009. PMID: 19146893

4

Strategies for Neoglycan conjugation to human acid α-glucosidase.

Zhou Q, Stefano JE, Harrahy J, Finn P, Avila L, Kyazike J, Wei R, Van Patten SM, Gotschall R, Zheng X, Zhu Y, Edmunds T, Pan CQ. Zhou Q, et al. Bioconjug Chem. 2011 Apr 20;22(4):741-51. doi: 10.1021/bc1005416. Epub 2011 Mar 18. Bioconjug Chem. 2011. PMID: 21417264

5

A bispecific protein capable of engaging CTLA-4 and MHCII protects non-obese diabetic mice from autoimmune diabetes.

Zhao H, Karman J, Jiang JL, Zhang J, Gumlaw N, Lydon J, Zhou Q, Qiu H, Jiang C, Cheng SH, Zhu Y. Zhao H, et al. Among authors: zhou q. PLoS One. 2013 May 21;8(5):e63530. doi: 10.1371/journal.pone.0063530. Print 2013. PLoS One. 2013. PMID: 23704916 Free PMC article.

6

Site-specific antibody-drug conjugation through glycoengineering.

Zhou Q, Stefano JE, Manning C, Kyazike J, Chen B, Gianolio DA, Park A, Busch M, Bird J, Zheng X, Simonds-Mannes H, Kim J, Gregory RC, Miller RJ, Brondyk WH, Dhal PK, Pan CQ. Zhou Q, et al. Bioconjug Chem. 2014 Mar 19;25(3):510-20. doi: 10.1021/bc400505q. Epub 2014 Feb 28. Bioconjug Chem. 2014. PMID: 24533768

7

The Mechanistic Impact of N-Glycosylation on Stability, Pharmacokinetics, and Immunogenicity of Therapeutic Proteins.

Zhou Q, Qiu H. Zhou Q, et al. J Pharm Sci. 2019 Apr;108(4):1366-1377. doi: 10.1016/j.xphs.2018.11.029. Epub 2018 Nov 22. J Pharm Sci. 2019. PMID: 30471292 Review.

8

Site-Specific Antibody Conjugation to Engineered Double Cysteine Residues.

Zhou Q, Kyazike J, Boudanova E, Drzyzga M, Honey D, Cost R, Hou L, Duffieux F, Brun MP, Park A, Qiu H. Zhou Q, et al. Pharmaceuticals (Basel). 2021 Jul 14;14(7):672. doi: 10.3390/ph14070672. Pharmaceuticals (Basel). 2021. PMID: 34358098 Free PMC article.

9

Targeted protein degradation through site-specific antibody conjugation with mannose 6-phosphate glycan.

Mukai K, Cost R, Zhang XS, Condiff E, Cotton J, Liu X, Boudanova E, Niebel B, Piepenhagen P, Cai X, Park A, Zhou Q. Mukai K, et al. Among authors: zhou q. MAbs. 2024 Jan-Dec;16(1):2415333. doi: 10.1080/19420862.2024.2415333. Epub 2024 Oct 21. MAbs. 2024. PMID: 39434219 Free PMC article.

10

Glycan structure determinants for cation-independent mannose 6-phosphate receptor binding and cellular uptake of a recombinant protein.

Zhou Q, Avila LZ, Konowicz PA, Harrahy J, Finn P, Kim J, Reardon MR, Kyazike J, Brunyak E, Zheng X, Patten SM, Miller RJ, Pan CQ. Zhou Q, et al. Bioconjug Chem. 2013 Dec 18;24(12):2025-35. doi: 10.1021/bc400365a. Epub 2013 Nov 12. Bioconjug Chem. 2013. PMID: 24161263

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