Quintieri L - Search Results

1

Midazolam oxidation in cattle liver microsomes: The role of cytochrome P450 3A.

Nassi A, Quintieri L, Merlanti R, Pezzato F, Capolongo F, Pauletto M, Dacasto M, Giantin M. Nassi A, et al. Among authors: quintieri l. J Vet Pharmacol Ther. 2020 Nov;43(6):608-613. doi: 10.1111/jvp.12906. Epub 2020 Sep 7. J Vet Pharmacol Ther. 2020. PMID: 32893906

2

Flavonoids diosmetin and luteolin inhibit midazolam metabolism by human liver microsomes and recombinant CYP 3A4 and CYP3A5 enzymes.

Quintieri L, Palatini P, Nassi A, Ruzza P, Floreani M. Quintieri L, et al. Biochem Pharmacol. 2008 Mar 15;75(6):1426-37. doi: 10.1016/j.bcp.2007.11.012. Epub 2007 Dec 4. Biochem Pharmacol. 2008. PMID: 18191104

3

Irreversible CYP3A inhibition accompanied by plasma protein-binding displacement: a comparative analysis in subjects with normal and impaired liver function.

Orlando R, De Martin S, Pegoraro P, Quintieri L, Palatini P. Orlando R, et al. Among authors: quintieri l. Clin Pharmacol Ther. 2009 Mar;85(3):319-26. doi: 10.1038/clpt.2008.216. Epub 2008 Nov 19. Clin Pharmacol Ther. 2009. PMID: 19020496 Clinical Trial.

4

Flavonoids diosmetin and hesperetin are potent inhibitors of cytochrome P450 2C9-mediated drug metabolism in vitro.

Quintieri L, Bortolozzo S, Stragliotto S, Moro S, Pavanetto M, Nassi A, Palatini P, Floreani M. Quintieri L, et al. Drug Metab Pharmacokinet. 2010;25(5):466-76. doi: 10.2133/dmpk.dmpk-10-rg-044. Epub 2010 Sep 22. Drug Metab Pharmacokinet. 2010. PMID: 20877134 Free article.

5

A Quantitative Approach to the Prediction of Drug-Drug Interactions Mediated by Cytochrome P450 2C8 Inhibition.

Di Paolo V, Ferrari FM, Poggesi I, Quintieri L. Di Paolo V, et al. Among authors: quintieri l. Expert Opin Drug Metab Toxicol. 2021 Nov;17(11):1345-1352. doi: 10.1080/17425255.2021.1998453. Epub 2021 Nov 2. Expert Opin Drug Metab Toxicol. 2021. PMID: 34720033

6

In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A.

Quintieri L, Rosato A, Napoli E, Sola F, Geroni C, Floreani M, Zanovello P. Quintieri L, et al. Cancer Res. 2000 Jun 15;60(12):3232-8. Cancer Res. 2000. PMID: 10866316

7

Formation and antitumor activity of PNU-159682, a major metabolite of nemorubicin in human liver microsomes.

Quintieri L, Geroni C, Fantin M, Battaglia R, Rosato A, Speed W, Zanovello P, Floreani M. Quintieri L, et al. Clin Cancer Res. 2005 Feb 15;11(4):1608-17. doi: 10.1158/1078-0432.CCR-04-1845. Clin Cancer Res. 2005. PMID: 15746066

8

In vitro hepatic conversion of the anticancer agent nemorubicin to its active metabolite PNU-159682 in mice, rats and dogs: a comparison with human liver microsomes.

Quintieri L, Fantin M, Palatini P, De Martin S, Rosato A, Caruso M, Geroni C, Floreani M. Quintieri L, et al. Biochem Pharmacol. 2008 Sep 15;76(6):784-95. doi: 10.1016/j.bcp.2008.07.003. Epub 2008 Jul 11. Biochem Pharmacol. 2008. PMID: 18671948

9

Synthesis and preliminary in vitro biological evaluation of 4-[(4-hydroxyphenyl)sulfanyl]but-3-en-2-one, a 4-mercaptophenol derivative designed as a novel bifunctional antimelanoma agent.

Ruzza P, Rosato A, Nassi A, Rondina M, Zorzin M, Rossi CR, Floreani M, Quintieri L. Ruzza P, et al. Among authors: quintieri l. J Med Chem. 2009 Aug 13;52(15):4973-6. doi: 10.1021/jm900642j. J Med Chem. 2009. PMID: 19601648

10

Quantitative Prediction of Drug Interactions Caused by Cytochrome P450 2B6 Inhibition or Induction.

Di Paolo V, Ferrari FM, Poggesi I, Quintieri L. Di Paolo V, et al. Among authors: quintieri l. Clin Pharmacokinet. 2022 Sep;61(9):1297-1306. doi: 10.1007/s40262-022-01153-y. Epub 2022 Jul 20. Clin Pharmacokinet. 2022. PMID: 35857278

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