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FcγRIIB engagement drives agonistic activity of Fc-engineered αOX40 antibody to stimulate human tumor-infiltrating T cells.
Campos Carrascosa L, van Beek AA, de Ruiter V, Doukas M, Wei J, Fisher TS, Ching K, Yang W, van Loon K, Boor PPC, Rakké YS, Noordam L, Doornebosch P, Grünhagen D, Verhoef K, Polak WG, IJzermans JNM, Ni I, Yeung YA, Salek-Ardakani S, Sprengers D, Kwekkeboom J. Campos Carrascosa L, et al. J Immunother Cancer. 2020 Sep;8(2):e000816. doi: 10.1136/jitc-2020-000816. J Immunother Cancer. 2020. PMID: 32900860 Free PMC article.
OX40 drives protective vaccinia virus-specific CD8 T cells.
Salek-Ardakani S, Moutaftsi M, Crotty S, Sette A, Croft M. Salek-Ardakani S, et al. J Immunol. 2008 Dec 1;181(11):7969-76. doi: 10.4049/jimmunol.181.11.7969. J Immunol. 2008. PMID: 19017988 Free PMC article.
CD40 agonist-induced IL-12p40 potentiates hepatotoxicity.
Bonnans C, Thomas G, He W, Jung B, Chen W, Liao M, Heyen J, Buetow B, Pillai S, Matsumoto D, Chaparro-Riggers J, Salek-Ardakani S, Qu Y. Bonnans C, et al. J Immunother Cancer. 2020 May;8(1):e000624. doi: 10.1136/jitc-2020-000624. J Immunother Cancer. 2020. PMID: 32474414 Free PMC article.
Pharmacologic Properties and Preclinical Activity of Sasanlimab, A High-affinity Engineered Anti-Human PD-1 Antibody.
Al-Khami AA, Youssef S, Abdiche Y, Nguyen H, Chou J, Kimberlin CR, Chin SM, Kamperschroer C, Jessen B, Kern B, Budimir N, Dillon CP, Xu A, Clark JD, Chou J, Kraynov E, Rajpal A, Lin JC, Salek-Ardakani S. Al-Khami AA, et al. Mol Cancer Ther. 2020 Oct;19(10):2105-2116. doi: 10.1158/1535-7163.MCT-20-0093. Epub 2020 Aug 26. Mol Cancer Ther. 2020. PMID: 32847983
Intra-Tumoral Activation of Endosomal TLR Pathways Reveals a Distinct Role for TLR3 Agonist Dependent Type-1 Interferons in Shaping the Tumor Immune Microenvironment.
Thomas G, Micci L, Yang W, Katakowski J, Oderup C, Sundar P, Wang X, Geles KG, Potluri S, Salek-Ardakani S. Thomas G, et al. Among authors: salek ardakani s. Front Oncol. 2021 Jul 26;11:711673. doi: 10.3389/fonc.2021.711673. eCollection 2021. Front Oncol. 2021. PMID: 34381732 Free PMC article.
84 results