Howells L - Search Results

1

Association of Type 2 Diabetes With Cancer: A Meta-analysis With Bias Analysis for Unmeasured Confounding in 151 Cohorts Comprising 32 Million People.

Ling S, Brown K, Miksza JK, Howells L, Morrison A, Issa E, Yates T, Khunti K, Davies MJ, Zaccardi F. Ling S, et al. Among authors: howells l. Diabetes Care. 2020 Sep;43(9):2313-2322. doi: 10.2337/dc20-0204. Diabetes Care. 2020. PMID: 32910779

2

Preclinical colorectal cancer chemopreventive efficacy and p53-modulating activity of 3',4',5'-trimethoxyflavonol, a quercetin analogue.

Howells LM, Britton RG, Mazzoletti M, Greaves P, Broggini M, Brown K, Steward WP, Gescher AJ, Sale S. Howells LM, et al. Cancer Prev Res (Phila). 2010 Aug;3(8):929-39. doi: 10.1158/1940-6207.CAPR-09-0236. Epub 2010 Jul 13. Cancer Prev Res (Phila). 2010. PMID: 20628003 Free PMC article.

3

Curcumin ameliorates oxaliplatin-induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo.

Howells LM, Sale S, Sriramareddy SN, Irving GR, Jones DJ, Ottley CJ, Pearson DG, Mann CD, Manson MM, Berry DP, Gescher A, Steward WP, Brown K. Howells LM, et al. Int J Cancer. 2011 Jul 15;129(2):476-86. doi: 10.1002/ijc.25670. Epub 2010 Nov 3. Int J Cancer. 2011. PMID: 20839263

4

The role of cancer stem cells in the anti-carcinogenicity of curcumin.

Norris L, Karmokar A, Howells L, Steward WP, Gescher A, Brown K. Norris L, et al. Among authors: howells l. Mol Nutr Food Res. 2013 Sep;57(9):1630-7. doi: 10.1002/mnfr.201300120. Epub 2013 Jul 31. Mol Nutr Food Res. 2013. PMID: 23900994 Review.

5

Translating curcumin to the clinic for lung cancer prevention: evaluation of the preclinical evidence for its utility in primary, secondary, and tertiary prevention strategies.

Howells LM, Mahale J, Sale S, McVeigh L, Steward WP, Thomas A, Brown K. Howells LM, et al. J Pharmacol Exp Ther. 2014 Sep;350(3):483-94. doi: 10.1124/jpet.114.216333. Epub 2014 Jun 17. J Pharmacol Exp Ther. 2014. PMID: 24939419 Free article. Review.

6

Cancer chemoprevention: factors influencing attitudes towards chemopreventive agents in high-risk populations.

Iwuji C, Howells L, Thomasset S, Brown K, Steward W, Barwell J, Thomas A. Iwuji C, et al. Among authors: howells l. Eur J Cancer Prev. 2014 Nov;23(6):594-601. doi: 10.1097/CEJ.0000000000000061. Eur J Cancer Prev. 2014. PMID: 25259886

7

The role of stromal fibroblasts in lung carcinogenesis: A target for chemoprevention?

Mahale J, Smagurauskaite G, Brown K, Thomas A, Howells LM. Mahale J, et al. Int J Cancer. 2016 Jan 1;138(1):30-44. doi: 10.1002/ijc.29447. Epub 2015 Feb 6. Int J Cancer. 2016. PMID: 25611701 Review.

8

Characterization and propagation of tumor initiating cells derived from colorectal liver metastases: trials, tribulations and a cautionary note.

James MI, Howells LM, Karmokar A, Higgins JA, Greaves P, Cai H, Dennison A, Metcalfe M, Garcea G, Lloyd DM, Berry DP, Steward WP, Brown K. James MI, et al. PLoS One. 2015 Feb 6;10(2):e0117776. doi: 10.1371/journal.pone.0117776. eCollection 2015. PLoS One. 2015. PMID: 25658706 Free PMC article.

9

Combining curcumin (C3-complex, Sabinsa) with standard care FOLFOX chemotherapy in patients with inoperable colorectal cancer (CUFOX): study protocol for a randomised control trial.

Irving GR, Iwuji CO, Morgan B, Berry DP, Steward WP, Thomas A, Brown K, Howells LM. Irving GR, et al. Trials. 2015 Mar 24;16:110. doi: 10.1186/s13063-015-0641-1. Trials. 2015. PMID: 25872567 Free PMC article. Clinical Trial.

10

Curcumin inhibits cancer stem cell phenotypes in ex vivo models of colorectal liver metastases, and is clinically safe and tolerable in combination with FOLFOX chemotherapy.

James MI, Iwuji C, Irving G, Karmokar A, Higgins JA, Griffin-Teal N, Thomas A, Greaves P, Cai H, Patel SR, Morgan B, Dennison A, Metcalfe M, Garcea G, Lloyd DM, Berry DP, Steward WP, Howells LM, Brown K. James MI, et al. Cancer Lett. 2015 Aug 10;364(2):135-41. doi: 10.1016/j.canlet.2015.05.005. Epub 2015 May 12. Cancer Lett. 2015. PMID: 25979230 Free PMC article. Clinical Trial.

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