Flygare J - Search Results

1

Metformin-induced suppression of Nemo-like kinase improves erythropoiesis in preclinical models of Diamond-Blackfan anemia through induction of miR-26a.

Wilkes MC, Siva K, Varetti G, Mercado J, Wentworth EP, Perez CA, Saxena M, Kam S, Kapur S, Chen J, Narla A, Glader B, Lin S, Serrano M, Flygare J, Sakamoto KM. Wilkes MC, et al. Among authors: flygare j. Exp Hematol. 2020 Nov;91:65-77. doi: 10.1016/j.exphem.2020.09.187. Epub 2020 Sep 12. Exp Hematol. 2020. PMID: 32926965 Free PMC article.

2

Proliferation deficiency of multipotent hematopoietic progenitors in ribosomal protein S19 (RPS19)-deficient diamond-Blackfan anemia improves following RPS19 gene transfer.

Hamaguchi I, Flygare J, Nishiura H, Brun AC, Ooka A, Kiefer T, Ma Z, Dahl N, Richter J, Karlsson S. Hamaguchi I, et al. Among authors: flygare j. Mol Ther. 2003 May;7(5 Pt 1):613-22. doi: 10.1016/s1525-0016(03)00091-1. Mol Ther. 2003. PMID: 12718904 Free article.

3

Deficiency of ribosomal protein S19 in CD34+ cells generated by siRNA blocks erythroid development and mimics defects seen in Diamond-Blackfan anemia.

Flygare J, Kiefer T, Miyake K, Utsugisawa T, Hamaguchi I, Da Costa L, Richter J, Davey EJ, Matsson H, Dahl N, Wiznerowicz M, Trono D, Karlsson S. Flygare J, et al. Blood. 2005 Jun 15;105(12):4627-34. doi: 10.1182/blood-2004-08-3115. Epub 2004 Dec 30. Blood. 2005. PMID: 15626736 Free article.

4

Development of cellular models for ribosomal protein S19 (RPS19)-deficient diamond-blackfan anemia using inducible expression of siRNA against RPS19.

Miyake K, Flygare J, Kiefer T, Utsugisawa T, Richter J, Ma Z, Wiznerowicz M, Trono D, Karlsson S. Miyake K, et al. Among authors: flygare j. Mol Ther. 2005 Apr;11(4):627-37. doi: 10.1016/j.ymthe.2004.12.001. Mol Ther. 2005. PMID: 15771965 Free article.

5

Erythropoiesis in the Rps19 disrupted mouse: Analysis of erythropoietin response and biochemical markers for Diamond-Blackfan anemia.

Matsson H, Davey EJ, Fröjmark AS, Miyake K, Utsugisawa T, Flygare J, Zahou E, Byman I, Landin B, Ronquist G, Karlsson S, Dahl N. Matsson H, et al. Among authors: flygare j. Blood Cells Mol Dis. 2006 Mar-Apr;36(2):259-64. doi: 10.1016/j.bcmd.2005.12.002. Epub 2006 Feb 7. Blood Cells Mol Dis. 2006. PMID: 16458028

6

Human RPS19, the gene mutated in Diamond-Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits.

Flygare J, Aspesi A, Bailey JC, Miyake K, Caffrey JM, Karlsson S, Ellis SR. Flygare J, et al. Blood. 2007 Feb 1;109(3):980-6. doi: 10.1182/blood-2006-07-038232. Epub 2006 Sep 21. Blood. 2007. PMID: 16990592 Free PMC article.

7

Diamond-Blackfan anemia: erythropoiesis lost in translation.

Flygare J, Karlsson S. Flygare J, et al. Blood. 2007 Apr 15;109(8):3152-4. doi: 10.1182/blood-2006-09-001222. Epub 2006 Dec 12. Blood. 2007. PMID: 17164339 Free article. Review.

8

Ribosomal protein S19 deficiency leads to reduced proliferation and increased apoptosis but does not affect terminal erythroid differentiation in a cell line model of Diamond-Blackfan anemia.

Miyake K, Utsugisawa T, Flygare J, Kiefer T, Hamaguchi I, Richter J, Karlsson S. Miyake K, et al. Among authors: flygare j. Stem Cells. 2008 Feb;26(2):323-9. doi: 10.1634/stemcells.2007-0569. Epub 2007 Oct 25. Stem Cells. 2008. PMID: 17962699

9

Gene therapy of Diamond Blackfan anemia CD34(+) cells leads to improved erythroid development and engraftment following transplantation.

Flygare J, Olsson K, Richter J, Karlsson S. Flygare J, et al. Exp Hematol. 2008 Nov;36(11):1428-35. doi: 10.1016/j.exphem.2008.06.012. Epub 2008 Aug 19. Exp Hematol. 2008. PMID: 18715690 Free article.

10

Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.

Jaako P, Flygare J, Olsson K, Quere R, Ehinger M, Henson A, Ellis S, Schambach A, Baum C, Richter J, Larsson J, Bryder D, Karlsson S. Jaako P, et al. Among authors: flygare j. Blood. 2011 Dec 1;118(23):6087-96. doi: 10.1182/blood-2011-08-371963. Epub 2011 Oct 11. Blood. 2011. PMID: 21989989 Free article.

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