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MACF1 controls skeletal muscle function through the microtubule-dependent localization of extra-synaptic myonuclei and mitochondria biogenesis.
Ghasemizadeh A, Christin E, Guiraud A, Couturier N, Abitbol M, Risson V, Girard E, Jagla C, Soler C, Laddada L, Sanchez C, Jaque-Fernandez FI, Jacquemond V, Thomas JL, Lanfranchi M, Courchet J, Gondin J, Schaeffer L, Gache V. Ghasemizadeh A, et al. Among authors: jagla c. Elife. 2021 Aug 27;10:e70490. doi: 10.7554/eLife.70490. Elife. 2021. PMID: 34448452 Free PMC article.
Mechanistic insights on clearance and inhibition discordance between liver microsomes and hepatocytes when clearance in liver microsomes is higher than in hepatocytes.
Keefer C, Chang G, Carlo A, Novak JJ, Banker M, Carey J, Cianfrogna J, Eng H, Jagla C, Johnson N, Jones R, Jordan S, Lazzaro S, Liu J, Scott Obach R, Riccardi K, Tess D, Umland J, Racich J, Varma M, Visswanathan R, Di L. Keefer C, et al. Among authors: jagla c. Eur J Pharm Sci. 2020 Dec 1;155:105541. doi: 10.1016/j.ejps.2020.105541. Epub 2020 Sep 12. Eur J Pharm Sci. 2020. PMID: 32927071
Methylnaltrexone and opioid analgesia.
Stein C, Jagla C. Stein C, et al. Among authors: jagla c. Pain. 2014 Dec;155(12):2722-2723. doi: 10.1016/j.pain.2014.09.008. Epub 2014 Sep 16. Pain. 2014. PMID: 25218602 No abstract available.