Kon R - Search Results

1

Effect of Astaxanthin on the Expression and Activity of Aquaporin-3 in Skin in an In-Vitro Study.

Ikarashi N, Kon R, Nagoya C, Ishikura A, Sugiyama Y, Takahashi J, Sugiyama K. Ikarashi N, et al. Among authors: kon r. Life (Basel). 2020 Sep 11;10(9):193. doi: 10.3390/life10090193. Life (Basel). 2020. PMID: 32932769 Free PMC article.

2

The laxative effect of bisacodyl is attributable to decreased aquaporin-3 expression in the colon induced by increased PGE2 secretion from macrophages.

Ikarashi N, Baba K, Ushiki T, Kon R, Mimura A, Toda T, Ishii M, Ochiai W, Sugiyama K. Ikarashi N, et al. Among authors: kon r. Am J Physiol Gastrointest Liver Physiol. 2011 Nov;301(5):G887-95. doi: 10.1152/ajpgi.00286.2011. Epub 2011 Aug 25. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21868635 Free article.

3

The concomitant use of an osmotic laxative, magnesium sulphate, and a stimulant laxative, bisacodyl, does not enhance the laxative effect.

Ikarashi N, Mimura A, Kon R, Iizasa T, Omodaka M, Nagoya C, Ishii M, Toda T, Ochiai W, Sugiyama K. Ikarashi N, et al. Among authors: kon r. Eur J Pharm Sci. 2012 Jan 23;45(1-2):73-8. doi: 10.1016/j.ejps.2011.10.024. Epub 2011 Nov 9. Eur J Pharm Sci. 2012. PMID: 22085681

4

Gypsum fibrosum and its major component CaSO4 increase cutaneous aquaporin-3 expression levels.

Ikarashi N, Ogiue N, Toyoda E, Kon R, Ishii M, Toda T, Aburada T, Ochiai W, Sugiyama K. Ikarashi N, et al. Among authors: kon r. J Ethnopharmacol. 2012 Jan 31;139(2):409-13. doi: 10.1016/j.jep.2011.11.025. Epub 2011 Nov 25. J Ethnopharmacol. 2012. PMID: 22138657

5

Consumption of a high-fat diet during pregnancy decreases the activity of cytochrome P450 3a in the livers of offspring.

Tajima M, Ikarashi N, Imahori Y, Okaniwa T, Saruta K, Ishii M, Kusunoki Y, Kon R, Toda T, Ochiai W, Yamada H, Sugiyama K. Tajima M, et al. Among authors: kon r. Eur J Pharm Sci. 2012 Aug 30;47(1):108-16. doi: 10.1016/j.ejps.2012.05.008. Epub 2012 May 30. Eur J Pharm Sci. 2012. PMID: 22659374

6

Inhibition of aquaporin-3 water channel in the colon induces diarrhea.

Ikarashi N, Kon R, Iizasa T, Suzuki N, Hiruma R, Suenaga K, Toda T, Ishii M, Hoshino M, Ochiai W, Sugiyama K. Ikarashi N, et al. Among authors: kon r. Biol Pharm Bull. 2012;35(6):957-62. doi: 10.1248/bpb.35.957. Biol Pharm Bull. 2012. PMID: 22687538 Free article.

7

Elucidating the mechanism by which Gypsum fibrosum, a traditional Chinese medicine, maintains cutaneous water content.

Ikarashi N, Ogiue N, Toyoda E, Nakamura M, Kon R, Kusunoki Y, Aburada T, Ishii M, Tanaka Y, Machida Y, Ochiai W, Sugiyama K. Ikarashi N, et al. Among authors: kon r. Biol Pharm Bull. 2013;36(10):1615-21. doi: 10.1248/bpb.b13-00494. Epub 2013 Aug 2. Biol Pharm Bull. 2013. PMID: 23912684 Free article.

8

Total gastrectomy may result in reduced drug effectiveness due to an increase in the expression of the drug-metabolizing enzyme Cytochrome P450, in the liver.

Ishii M, Toda T, Ikarashi N, Kusunoki Y, Kon R, Ochiai W, Machida Y, Sugiyama K. Ishii M, et al. Among authors: kon r. Eur J Pharm Sci. 2014 Jan 23;51:180-8. doi: 10.1016/j.ejps.2013.09.017. Epub 2013 Oct 3. Eur J Pharm Sci. 2014. PMID: 24095864

9

Gastrectomy increases the expression of hepatic cytochrome P450 3A by increasing lithocholic acid-producing enteric bacteria in mice.

Ishii M, Toda T, Ikarashi N, Kusunoki Y, Kon R, Ochiai W, Machida Y, Sugiyama K. Ishii M, et al. Among authors: kon r. Biol Pharm Bull. 2014;37(2):298-305. doi: 10.1248/bpb.b13-00824. Epub 2013 Nov 23. Biol Pharm Bull. 2014. PMID: 24270587 Free article.

10

Rheinanthrone, a metabolite of sennoside A, triggers macrophage activation to decrease aquaporin-3 expression in the colon, causing the laxative effect of rhubarb extract.

Kon R, Ikarashi N, Nagoya C, Takayama T, Kusunoki Y, Ishii M, Ueda H, Ochiai W, Machida Y, Sugita K, Sugiyama K. Kon R, et al. J Ethnopharmacol. 2014 Feb 27;152(1):190-200. doi: 10.1016/j.jep.2013.12.055. Epub 2014 Jan 8. J Ethnopharmacol. 2014. PMID: 24412547

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