Imbimbo BP - Search Results

1

Effects of Topical Application of CHF6467, a Mutated Form of Human Nerve Growth Factor, on Skin Wound Healing in Diabetic Mice.

Giuliani A, Lorenzini L, Baldassarro VA, Pannella M, Cescatti M, Fernandez M, Alastra G, Flagelli A, Villetti G, Imbimbo BP, Giardino L, Calzà L. Giuliani A, et al. Among authors: imbimbo bp. J Pharmacol Exp Ther. 2020 Nov;375(2):317-331. doi: 10.1124/jpet.120.000110. Epub 2020 Sep 18. J Pharmacol Exp Ther. 2020. PMID: 32948647

2

Ganstigmine and donepezil improve neurodegeneration in AD11 antinerve growth factor transgenic mice.

Capsoni S, Giannotta S, Stebel M, Garcia AA, De Rosa R, Villetti G, Imbimbo BP, Pietra C, Cattaneo A. Capsoni S, et al. Among authors: imbimbo bp. Am J Alzheimers Dis Other Demen. 2004 May-Jun;19(3):153-60. doi: 10.1177/153331750401900303. Am J Alzheimers Dis Other Demen. 2004. PMID: 15214201 Free PMC article.

3

Conformation-sensitive antibodies against alzheimer amyloid-beta by immunization with a thioredoxin-constrained B-cell epitope peptide.

Moretto N, Bolchi A, Rivetti C, Imbimbo BP, Villetti G, Pietrini V, Polonelli L, Del Signore S, Smith KM, Ferrante RJ, Ottonello S. Moretto N, et al. Among authors: imbimbo bp. J Biol Chem. 2007 Apr 13;282(15):11436-45. doi: 10.1074/jbc.M609690200. Epub 2007 Jan 31. J Biol Chem. 2007. PMID: 17267402 Free article.

4

In vitro and in vivo profiling of CHF5022 and CHF5074 Two beta-amyloid1-42 lowering agents.

Imbimbo BP, Del Giudice E, Cenacchi V, Volta R, Villetti G, Facchinetti F, Riccardi B, Puccini P, Moretto N, Grassi F, Ottonello S, Leon A. Imbimbo BP, et al. Pharmacol Res. 2007 Apr;55(4):318-28. doi: 10.1016/j.phrs.2006.12.010. Epub 2007 Jan 16. Pharmacol Res. 2007. PMID: 17292621

5

1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid (CHF5074), a novel gamma-secretase modulator, reduces brain beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease without causing peripheral toxicity.

Imbimbo BP, Del Giudice E, Colavito D, D'Arrigo A, Dalle Carbonare M, Villetti G, Facchinetti F, Volta R, Pietrini V, Baroc MF, Serneels L, De Strooper B, Leon A. Imbimbo BP, et al. J Pharmacol Exp Ther. 2007 Dec;323(3):822-30. doi: 10.1124/jpet.107.129007. Epub 2007 Sep 25. J Pharmacol Exp Ther. 2007. PMID: 17895400

6

CHF5074, a novel gamma-secretase modulator, attenuates brain beta-amyloid pathology and learning deficit in a mouse model of Alzheimer's disease.

Imbimbo BP, Hutter-Paier B, Villetti G, Facchinetti F, Cenacchi V, Volta R, Lanzillotta A, Pizzi M, Windisch M. Imbimbo BP, et al. Br J Pharmacol. 2009 Mar;156(6):982-93. doi: 10.1111/j.1476-5381.2008.00097.x. Br J Pharmacol. 2009. PMID: 19239474 Free PMC article.

7

CHF5074, a novel gamma-secretase modulator, restores hippocampal neurogenesis potential and reverses contextual memory deficit in a transgenic mouse model of Alzheimer's disease.

Imbimbo BP, Giardino L, Sivilia S, Giuliani A, Gusciglio M, Pietrini V, Del Giudice E, D'Arrigo A, Leon A, Villetti G, Calzà L. Imbimbo BP, et al. J Alzheimers Dis. 2010;20(1):159-73. doi: 10.3233/JAD-2010-1366. J Alzheimers Dis. 2010. PMID: 20164581

8

The γ-secretase modulator CHF5074 restores memory and hippocampal synaptic plasticity in plaque-free Tg2576 mice.

Balducci C, Mehdawy B, Mare L, Giuliani A, Lorenzini L, Sivilia S, Giardino L, Calzà L, Lanzillotta A, Sarnico I, Pizzi M, Usiello A, Viscomi AR, Ottonello S, Villetti G, Imbimbo BP, Nisticò G, Forloni G, Nisticò R. Balducci C, et al. Among authors: imbimbo bp. J Alzheimers Dis. 2011;24(4):799-816. doi: 10.3233/JAD-2011-101839. J Alzheimers Dis. 2011. PMID: 21321397

9

Pharmacokinetics and pharmacodynamics of CHF5074 after short-term administration in healthy subjects.

Imbimbo BP, Frigerio E, Breda M, Fiorentini F, Fernandez M, Sivilia S, Giardino L, Calzà L, Norris D, Casula D, Shenouda M. Imbimbo BP, et al. Alzheimer Dis Assoc Disord. 2013 Jul-Sep;27(3):278-86. doi: 10.1097/WAD.0b013e3182622ace. Alzheimer Dis Assoc Disord. 2013. PMID: 22922591 Clinical Trial.

10

CHF5074 restores visual memory ability and pre-synaptic cortical acetylcholine release in pre-plaque Tg2576 mice.

Giuliani A, Beggiato S, Baldassarro VA, Mangano C, Giardino L, Imbimbo BP, Antonelli T, Calzà L, Ferraro L. Giuliani A, et al. Among authors: imbimbo bp. J Neurochem. 2013 Mar;124(5):613-20. doi: 10.1111/jnc.12136. Epub 2013 Jan 28. J Neurochem. 2013. PMID: 23278303 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

246 results

Search Page

Filters