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Page 1
Influenza A virus causes maternal and fetal pathology via innate and adaptive vascular inflammation in mice.
Liong S, Oseghale O, To EE, Brassington K, Erlich JR, Luong R, Liong F, Brooks R, Martin C, O'Toole S, Vinh A, O'Neill LAJ, Bozinovski S, Vlahos R, Papagianis PC, O'Leary JJ, Brooks DA, Selemidis S. Liong S, et al. Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):24964-24973. doi: 10.1073/pnas.2006905117. Epub 2020 Sep 21. Proc Natl Acad Sci U S A. 2020. PMID: 32958663 Free PMC article.
NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.
Miggin SM, Pålsson-McDermott E, Dunne A, Jefferies C, Pinteaux E, Banahan K, Murphy C, Moynagh P, Yamamoto M, Akira S, Rothwell N, Golenbock D, Fitzgerald KA, O'Neill LA. Miggin SM, et al. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3372-7. doi: 10.1073/pnas.0608100104. Epub 2007 Feb 20. Proc Natl Acad Sci U S A. 2007. PMID: 17360653 Free PMC article.
The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer.
d'Adhemar CJ, Spillane CD, Gallagher MF, Bates M, Costello KM, Barry-O'Crowley J, Haley K, Kernan N, Murphy C, Smyth PC, O'Byrne K, Pennington S, Cooke AA, Ffrench B, Martin CM, O'Donnell D, Hennessy B, Stordal B, Finn S, McCann A, Gleeson N, D'Arcy T, Flood B, O'Neill LA, Sheils O, O'Toole S, O'Leary JJ. d'Adhemar CJ, et al. PLoS One. 2014 Jun 30;9(6):e100816. doi: 10.1371/journal.pone.0100816. eCollection 2014. PLoS One. 2014. PMID: 24977712 Free PMC article.
Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1.
Curtis AM, Fagundes CT, Yang G, Palsson-McDermott EM, Wochal P, McGettrick AF, Foley NH, Early JO, Chen L, Zhang H, Xue C, Geiger SS, Hokamp K, Reilly MP, Coogan AN, Vigorito E, FitzGerald GA, O'Neill LA. Curtis AM, et al. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7231-6. doi: 10.1073/pnas.1501327112. Epub 2015 May 20. Proc Natl Acad Sci U S A. 2015. PMID: 25995365 Free PMC article.
Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy.
To EE, Vlahos R, Luong R, Halls ML, Reading PC, King PT, Chan C, Drummond GR, Sobey CG, Broughton BRS, Starkey MR, van der Sluis R, Lewin SR, Bozinovski S, O'Neill LAJ, Quach T, Porter CJH, Brooks DA, O'Leary JJ, Selemidis S. To EE, et al. Nat Commun. 2017 Jul 12;8(1):69. doi: 10.1038/s41467-017-00057-x. Nat Commun. 2017. PMID: 28701733 Free PMC article.
MyD88 is an essential component of retinoic acid-induced differentiation in human pluripotent embryonal carcinoma cells.
Sulaiman G, Cooke A, Ffrench B, Gasch C, Abdullai OA, O'Connor K, Elbaruni S, Blackshields G, Spillane C, Keegan H, McEneaney V, Knittel R, Rogers A, Jeffery IB, Doyle B, Bates M, d'Adhemar C, Lee MY, Campbell EL, Moynagh PN, Higgins DG, O'Toole S, O'Neill L, O'Leary JJ, Gallagher MF. Sulaiman G, et al. Cell Death Differ. 2017 Nov;24(11):1975-1986. doi: 10.1038/cdd.2017.124. Epub 2017 Sep 8. Cell Death Differ. 2017. PMID: 28885616 Free PMC article.
445 results