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Aspirin Rescues Wnt-Driven Stem-like Phenotype in Human Intestinal Organoids and Increases the Wnt Antagonist Dickkopf-1.
Dunbar K, Valanciute A, Lima ACS, Vinuela PF, Jamieson T, Rajasekaran V, Blackmur J, Ochocka-Fox AM, Guazzelli A, Cammareri P, Arends MJ, Sansom OJ, Myant KB, Farrington SM, Dunlop MG, Din FVN. Dunbar K, et al. Among authors: arends mj. Cell Mol Gastroenterol Hepatol. 2021;11(2):465-489. doi: 10.1016/j.jcmgh.2020.09.010. Epub 2020 Sep 22. Cell Mol Gastroenterol Hepatol. 2021. PMID: 32971322 Free PMC article.
Mutationally activated K-ras 4A and 4B both mediate lung carcinogenesis.
Patek CE, Arends MJ, Wallace WA, Luo F, Hagan S, Brownstein DG, Rose L, Devenney PS, Walker M, Plowman SJ, Berry RL, Kolch W, Sansom OJ, Harrison DJ, Hooper ML. Patek CE, et al. Among authors: arends mj. Exp Cell Res. 2008 Mar 10;314(5):1105-14. doi: 10.1016/j.yexcr.2007.11.004. Epub 2007 Nov 17. Exp Cell Res. 2008. PMID: 18062963
Genome-wide in vivo screen identifies novel host regulators of metastatic colonization.
van der Weyden L, Arends MJ, Campbell AD, Bald T, Wardle-Jones H, Griggs N, Velasco-Herrera MD, Tüting T, Sansom OJ, Karp NA, Clare S, Gleeson D, Ryder E, Galli A, Tuck E, Cambridge EL, Voet T, Macaulay IC, Wong K; Sanger Mouse Genetics Project; Spiegel S, Speak AO, Adams DJ. van der Weyden L, et al. Among authors: arends mj. Nature. 2017 Jan 12;541(7636):233-236. doi: 10.1038/nature20792. Epub 2017 Jan 4. Nature. 2017. PMID: 28052056 Free PMC article.
CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation.
van der Weyden L, Harle V, Turner G, Offord V, Iyer V, Droop A, Swiatkowska A, Rabbie R, Campbell AD, Sansom OJ, Pardo M, Choudhary JS, Ferreira I, Tullett M, Arends MJ, Speak AO, Adams DJ. van der Weyden L, et al. Among authors: arends mj. Commun Biol. 2021 Mar 23;4(1):395. doi: 10.1038/s42003-021-01912-w. Commun Biol. 2021. PMID: 33758365 Free PMC article.
Loss of DOCK2 potentiates Inflammatory Bowel Disease-associated colorectal cancer via immune dysfunction and IFNγ induction of IDO1 expression.
Churchhouse AMD, Billard CV, Suzuki T, Pohl SÖG, Doleschall NJ, Donnelly K, Nixon C, Arends MJ, Din S, Kirkwood K, Marques Junior J, Von Kriegsheim A, Coffelt SB, Myant KB. Churchhouse AMD, et al. Among authors: arends mj. Oncogene. 2024 Oct;43(42):3094-3107. doi: 10.1038/s41388-024-03135-9. Epub 2024 Sep 7. Oncogene. 2024. PMID: 39242821 Free PMC article.
213 results