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Phase I clinical trial repurposing all-trans retinoic acid as a stromal targeting agent for pancreatic cancer.
Kocher HM, Basu B, Froeling FEM, Sarker D, Slater S, Carlin D, deSouza NM, De Paepe KN, Goulart MR, Hughes C, Imrali A, Roberts R, Pawula M, Houghton R, Lawrence C, Yogeswaran Y, Mousa K, Coetzee C, Sasieni P, Prendergast A, Propper DJ. Kocher HM, et al. Among authors: hughes c. Nat Commun. 2020 Sep 24;11(1):4841. doi: 10.1038/s41467-020-18636-w. Nat Commun. 2020. PMID: 32973176 Free PMC article. Clinical Trial.
Validation of a Novel, Flash-Freezing Method: Aluminum Platform.
Imrali A, Hughes CS, Coetzee AS, Delvecchio FR, Saad A, Roberts R, Chelala C, ChinAleong JA, Kocher HM. Imrali A, et al. Among authors: hughes cs. Curr Protoc Essent Lab Tech. 2020 Dec;21(1):e46. doi: 10.1002/cpet.46. Epub 2020 Nov 25. Curr Protoc Essent Lab Tech. 2020. PMID: 33381282 Free PMC article.
Pentraxin 3 is a stromally-derived biomarker for detection of pancreatic ductal adenocarcinoma.
Goulart MR, Watt J, Siddiqui I, Lawlor RT, Imrali A, Hughes C, Saad A, ChinAleong J, Hurt C, Cox C, Salvia R, Mantovani A, Crnogorac-Jurcevic T, Mukherjee S, Scarpa A, Allavena P, Kocher HM. Goulart MR, et al. Among authors: hughes c. NPJ Precis Oncol. 2021 Jun 29;5(1):61. doi: 10.1038/s41698-021-00192-1. NPJ Precis Oncol. 2021. PMID: 34188166 Free PMC article.
WILL (When to Induce Labour to Limit risk in pregnancy hypertension): a multicentre randomised controlled trial - adaptations to deliver a timing-of-birth trial during the COVID-19 international pandemic.
Magee LA, Tohill S, Kirkham K, Evans R, Gkini E, Moakes CA, Stubbs C, Thornton J, von Dadelszen P; WILL Trial Study Group. Magee LA, et al. Trials. 2022 Oct 21;23(1):884. doi: 10.1186/s13063-022-06834-4. Trials. 2022. PMID: 36271441 Free PMC article. Clinical Trial.
A multicentre, randomised controlled trial to compare the clinical and cost-effectiveness of Lee Silverman Voice Treatment versus standard NHS Speech and Language Therapy versus control in Parkinson's disease: a study protocol for a randomised controlled trial.
Sackley CM, Rick C, Au P, Brady MC, Beaton G, Burton C, Caulfield M, Dickson S, Dowling F, Hughes M, Ives N, Jowett S, Masterson-Algar P, Nicoll A, Patel S, Smith CH, Woolley R, Clarke CE; PD COMM Collaborative Group. Sackley CM, et al. Among authors: hughes m. Trials. 2020 May 27;21(1):436. doi: 10.1186/s13063-020-04354-7. Trials. 2020. PMID: 32460885 Free PMC article.
Glucose Lowering through Weight management (GLoW): a randomised controlled trial of the clinical and cost effectiveness of a diabetes education and behavioural weight management programme vs a diabetes education programme in adults with a recent diagnosis of type 2 diabetes.
Mueller J, Breeze P, Fusco F, Sharp SJ, Pidd K, Brennan A, Hill AJ, Morris S, Hughes CA, Bates SE, Pollard D, Woolston J, Lachassseigne E, Stubbings M, Whittle F, Jones RA, Boothby CE, Duschinsky R, Bostock J, Islam N, Griffin SJ, Ahern AL. Mueller J, et al. Among authors: hughes ca. Diabetologia. 2025 Jan 23. doi: 10.1007/s00125-024-06355-6. Online ahead of print. Diabetologia. 2025. PMID: 39849151
3,932 results