Ottolenghi S - Search Results

1

Sox2-dependent maintenance of mouse oligodendroglioma involves the Sox2-mediated downregulation of Cdkn2b, Ebf1, Zfp423, and Hey2.

Barone C, Buccarelli M, Alessandrini F, Pagin M, Rigoldi L, Sambruni I, Favaro R, Ottolenghi S, Pallini R, Ricci-Vitiani L, Malatesta P, Nicolis SK. Barone C, et al. Among authors: ottolenghi s. Glia. 2021 Mar;69(3):579-593. doi: 10.1002/glia.23914. Epub 2020 Sep 25. Glia. 2021. PMID: 32975900

2

Sox2 is required to maintain cancer stem cells in a mouse model of high-grade oligodendroglioma.

Favaro R, Appolloni I, Pellegatta S, Sanga AB, Pagella P, Gambini E, Pisati F, Ottolenghi S, Foti M, Finocchiaro G, Malatesta P, Nicolis SK. Favaro R, et al. Among authors: ottolenghi s. Cancer Res. 2014 Mar 15;74(6):1833-44. doi: 10.1158/0008-5472.CAN-13-1942. Epub 2014 Mar 5. Cancer Res. 2014. PMID: 24599129 Free article.

3

Sox2 conditional mutation in mouse causes ataxic symptoms, cerebellar vermis hypoplasia, and postnatal defects of Bergmann glia.

Cerrato V, Mercurio S, Leto K, Fucà E, Hoxha E, Bottes S, Pagin M, Milanese M, Ngan CY, Concina G, Ottolenghi S, Wei CL, Bonanno G, Pavesi G, Tempia F, Buffo A, Nicolis SK. Cerrato V, et al. Among authors: ottolenghi s. Glia. 2018 Sep;66(9):1929-1946. doi: 10.1002/glia.23448. Epub 2018 May 6. Glia. 2018. PMID: 29732603 Free article.

4

Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh.

Favaro R, Valotta M, Ferri AL, Latorre E, Mariani J, Giachino C, Lancini C, Tosetti V, Ottolenghi S, Taylor V, Nicolis SK. Favaro R, et al. Among authors: ottolenghi s. Nat Neurosci. 2009 Oct;12(10):1248-56. doi: 10.1038/nn.2397. Epub 2009 Sep 6. Nat Neurosci. 2009. PMID: 19734891

5

Sox2 is required for embryonic development of the ventral telencephalon through the activation of the ventral determinants Nkx2.1 and Shh.

Ferri A, Favaro R, Beccari L, Bertolini J, Mercurio S, Nieto-Lopez F, Verzeroli C, La Regina F, De Pietri Tonelli D, Ottolenghi S, Bovolenta P, Nicolis SK. Ferri A, et al. Among authors: ottolenghi s. Development. 2013 Mar;140(6):1250-61. doi: 10.1242/dev.073411. Development. 2013. PMID: 23444355

6

Mapping the Global Chromatin Connectivity Network for Sox2 Function in Neural Stem Cell Maintenance.

Bertolini JA, Favaro R, Zhu Y, Pagin M, Ngan CY, Wong CH, Tjong H, Vermunt MW, Martynoga B, Barone C, Mariani J, Cardozo MJ, Tabanera N, Zambelli F, Mercurio S, Ottolenghi S, Robson P, Creyghton MP, Bovolenta P, Pavesi G, Guillemot F, Nicolis SK, Wei CL. Bertolini JA, et al. Among authors: ottolenghi s. Cell Stem Cell. 2019 Mar 7;24(3):462-476.e6. doi: 10.1016/j.stem.2019.02.004. Cell Stem Cell. 2019. PMID: 30849367 Free PMC article.

7

Sox2 controls neural stem cell self-renewal through a Fos-centered gene regulatory network.

Pagin M, Pernebrink M, Giubbolini S, Barone C, Sambruni G, Zhu Y, Chiara M, Ottolenghi S, Pavesi G, Wei CL, Cantù C, Nicolis SK. Pagin M, et al. Among authors: ottolenghi s. Stem Cells. 2021 Aug;39(8):1107-1119. doi: 10.1002/stem.3373. Epub 2021 Mar 29. Stem Cells. 2021. PMID: 33739574

8

FOS Rescues Neuronal Differentiation of Sox2-Deleted Neural Stem Cells by Genome-Wide Regulation of Common SOX2 and AP1(FOS-JUN) Target Genes.

Pagin M, Pernebrink M, Pitasi M, Malighetti F, Ngan CY, Ottolenghi S, Pavesi G, Cantù C, Nicolis SK. Pagin M, et al. Among authors: ottolenghi s. Cells. 2021 Jul 12;10(7):1757. doi: 10.3390/cells10071757. Cells. 2021. PMID: 34359927 Free PMC article.

9

Emx2 is a dose-dependent negative regulator of Sox2 telencephalic enhancers.

Mariani J, Favaro R, Lancini C, Vaccari G, Ferri AL, Bertolini J, Tonoli D, Latorre E, Caccia R, Ronchi A, Ottolenghi S, Miyagi S, Okuda A, Zappavigna V, Nicolis SK. Mariani J, et al. Among authors: ottolenghi s. Nucleic Acids Res. 2012 Aug;40(14):6461-76. doi: 10.1093/nar/gks295. Epub 2012 Apr 11. Nucleic Acids Res. 2012. PMID: 22495934 Free PMC article.

10

Conserved POU binding DNA sites in the Sox2 upstream enhancer regulate gene expression in embryonic and neural stem cells.

Catena R, Tiveron C, Ronchi A, Porta S, Ferri A, Tatangelo L, Cavallaro M, Favaro R, Ottolenghi S, Reinbold R, Schöler H, Nicolis SK. Catena R, et al. Among authors: ottolenghi s. J Biol Chem. 2004 Oct 1;279(40):41846-57. doi: 10.1074/jbc.M405514200. Epub 2004 Jul 15. J Biol Chem. 2004. PMID: 15262984 Free article.

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