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Page 1
Priming of Anti-tumor Immune Mechanisms by Radiotherapy Is Augmented by Inhibition of Heat Shock Protein 90.
Ernst A, Hennel R, Krombach J, Kapfhammer H, Brix N, Zuchtriegel G, Uhl B, Reichel CA, Frey B, Gaipl US, Winssinger N, Shirasawa S, Sasazuki T, Sperandio M, Belka C, Lauber K. Ernst A, et al. Among authors: winssinger n. Front Oncol. 2020 Aug 27;10:1668. doi: 10.3389/fonc.2020.01668. eCollection 2020. Front Oncol. 2020. PMID: 32984042 Free PMC article.
Target-Accelerated Combinatorial Synthesis and Discovery of Highly Potent Antibiotics Effective Against Vancomycin-Resistant Bacteria.
Nicolaou KC, Hughes R, Cho SY, Winssinger N, Smethurst C, Labischinski H, Endermann R. Nicolaou KC, et al. Among authors: winssinger n. Angew Chem Int Ed Engl. 2000 Nov 3;39(21):3823-3828. doi: 10.1002/1521-3773(20001103)39:21<3823::AID-ANIE3823>3.0.CO;2-3. Angew Chem Int Ed Engl. 2000. PMID: 29711708 No abstract available.
A novel HSP90 inhibitor with reduced hepatotoxicity synergizes with radiotherapy to induce apoptosis, abrogate clonogenic survival, and improve tumor control in models of colorectal cancer.
Kinzel L, Ernst A, Orth M, Albrecht V, Hennel R, Brix N, Frey B, Gaipl US, Zuchtriegel G, Reichel CA, Blutke A, Schilling D, Multhoff G, Li M, Niyazi M, Friedl AA, Winssinger N, Belka C, Lauber K. Kinzel L, et al. Among authors: winssinger n. Oncotarget. 2016 Jul 12;7(28):43199-43219. doi: 10.18632/oncotarget.9774. Oncotarget. 2016. PMID: 27259245 Free PMC article.
Inhibition of HSP90 as a Strategy to Radiosensitize Glioblastoma: Targeting the DNA Damage Response and Beyond.
Orth M, Albrecht V, Seidl K, Kinzel L, Unger K, Hess J, Kreutzer L, Sun N, Stegen B, Nieto A, Maas J, Winssinger N, Friedl AA, Walch AK, Belka C, Zitzelsberger H, Niyazi M, Lauber K. Orth M, et al. Among authors: winssinger n. Front Oncol. 2021 Mar 17;11:612354. doi: 10.3389/fonc.2021.612354. eCollection 2021. Front Oncol. 2021. PMID: 33816244 Free PMC article.
Luciferase Controlled Protein Interactions.
Chang D, Feng S, Girik V, Riezman H, Winssinger N. Chang D, et al. Among authors: winssinger n. J Am Chem Soc. 2021 Mar 17;143(10):3665-3670. doi: 10.1021/jacs.0c11016. Epub 2021 Mar 8. J Am Chem Soc. 2021. PMID: 33684293
Synthesis of Protein-Oligonucleotide Conjugates.
Watson EE, Winssinger N. Watson EE, et al. Among authors: winssinger n. Biomolecules. 2022 Oct 20;12(10):1523. doi: 10.3390/biom12101523. Biomolecules. 2022. PMID: 36291732 Free PMC article. Review.
Novel PTP1B inhibitors identified by DNA display of fragment pairs.
Barluenga S, Zambaldo C, Ioannidou HA, Ciobanu M, Morieux P, Daguer JP, Winssinger N. Barluenga S, et al. Among authors: winssinger n. Bioorg Med Chem Lett. 2016 Feb 1;26(3):1080-1085. doi: 10.1016/j.bmcl.2015.11.102. Epub 2015 Nov 28. Bioorg Med Chem Lett. 2016. PMID: 26691757
161 results