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RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice.
Karunakaran D, Turner AW, Duchez AC, Soubeyrand S, Rasheed A, Smyth D, Cook DP, Nikpay M, Kandiah JW, Pan C, Geoffrion M, Lee R, Boytard L, Wyatt H, Nguyen MA, Lau P, Laakso M, Ramkhelawon B, Alvarez M, Pietiläinen KH, Pajukanta P, Vanderhyden BC, Liu P, Berger SB, Gough PJ, Bertin J, Harper ME, Lusis AJ, McPherson R, Rayner KJ. Karunakaran D, et al. Among authors: mcpherson r. Nat Metab. 2020 Oct;2(10):1113-1125. doi: 10.1038/s42255-020-00279-2. Epub 2020 Sep 28. Nat Metab. 2020. PMID: 32989316 Free PMC article.
UCP3 and its putative function: consistencies and controversies.
Harper ME, Dent RM, Bezaire V, Antoniou A, Gauthier A, Monemdjou S, McPherson R. Harper ME, et al. Among authors: mcpherson r. Biochem Soc Trans. 2001 Nov;29(Pt 6):768-73. doi: 10.1042/bst0290768. Biochem Soc Trans. 2001. PMID: 11709072 Review.
998 results