Topletz-Erickson AR - Search Results

1

Tucatinib Inhibits Renal Transporters OCT2 and MATE Without Impacting Renal Function in Healthy Subjects.

Topletz-Erickson AR, Lee AJ, Mayor JG, Rustia EL, Abdulrasool LI, Wise AL, Dailey B, DeChenne S, Walker LN, Alley SC, Endres CJ. Topletz-Erickson AR, et al. J Clin Pharmacol. 2021 Apr;61(4):461-471. doi: 10.1002/jcph.1750. Epub 2020 Sep 28. J Clin Pharmacol. 2021. PMID: 32989831 Free PMC article. Clinical Trial.

2

Evaluation of Safety and Clinically Relevant Drug-Drug Interactions with Tucatinib in Healthy Volunteers.

Topletz-Erickson A, Lee A, Rustia EL, Sun H, Mayor JG, Abdulrasool LI, Walker L, Endres CJ. Topletz-Erickson A, et al. Clin Pharmacokinet. 2022 Oct;61(10):1417-1426. doi: 10.1007/s40262-022-01144-z. Epub 2022 Aug 6. Clin Pharmacokinet. 2022. PMID: 35931943 Free PMC article.

3

Elimination of tucatinib, a small molecule kinase inhibitor of HER2, is primarily governed by CYP2C8 enantioselective oxidation of gem-dimethyl.

Sun H, Cardinal KA, Wienkers L, Chin A, Kumar V, Neace C, Henderson C, Endres CJ, Topletz-Erickson A, Regal K, Vo A, Alley SC, Lee AJ. Sun H, et al. Cancer Chemother Pharmacol. 2022 Jun;89(6):737-750. doi: 10.1007/s00280-022-04429-z. Epub 2022 Apr 18. Cancer Chemother Pharmacol. 2022. PMID: 35435471

4

A modelling approach to compare ADC deconjugation and systemic elimination rates of individual drug-load species using native ADC LC-MS data from human plasma.

Hengel SM, Topletz-Erickson AR, Kadry H, Alley SC. Hengel SM, et al. Among authors: topletz erickson ar. Xenobiotica. 2024 Aug;54(8):492-501. doi: 10.1080/00498254.2024.2340741. Epub 2024 Sep 27. Xenobiotica. 2024. PMID: 39329288 Free article.

5

Creation of Novel Sensitive Probe Substrate and Moderate Inhibitor Models for a Comprehensive Prediction of CYP2C8 Interactions for Tucatinib.

Templeton IE, Rowland-Yeo K, Jones HM, Endres CJ, Topletz-Erickson AR, Sun H, Lee AJ. Templeton IE, et al. Among authors: topletz erickson ar. Clin Pharmacol Ther. 2024 Feb;115(2):299-308. doi: 10.1002/cpt.3104. Epub 2023 Dec 8. Clin Pharmacol Ther. 2024. PMID: 37971208

6

Effect of Tucatinib on Cardiac Repolarization in Healthy Volunteers.

Topletz-Erickson AR, Mayor JG, Liu HT, Abdulrasool LI, Endres CJ. Topletz-Erickson AR, et al. Drugs R D. 2023 Dec;23(4):411-419. doi: 10.1007/s40268-023-00440-8. Epub 2023 Sep 26. Drugs R D. 2023. PMID: 37751113 Free PMC article. Clinical Trial.

7

The Pharmacokinetics and Safety of Tucatinib in Volunteers with Hepatic Impairment.

Topletz-Erickson AR, Lee AJ, Mayor JG, Sun H, Abdulrasool LI, Rustia EL, Walker LN, Endres CJ. Topletz-Erickson AR, et al. Clin Pharmacokinet. 2022 Dec;61(12):1761-1770. doi: 10.1007/s40262-022-01183-6. Epub 2022 Dec 5. Clin Pharmacokinet. 2022. PMID: 36471222 Free PMC article. Clinical Trial.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

7 results

Search Page

Filters