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Valproate treatment of human cord blood CD4-positive effector T cells confers on them the molecular profile (microRNA signature and FOXP3 expression) of natural regulatory CD4-positive cells through inhibition of histone deacetylase.
Fayyad-Kazan H, Rouas R, Merimi M, El Zein N, Lewalle P, Jebbawi F, Mourtada M, Badran H, Ezzeddine M, Salaun B, Romero P, Burny A, Martiat P, Badran B. Fayyad-Kazan H, et al. J Biol Chem. 2010 Jul 2;285(27):20481-91. doi: 10.1074/jbc.M110.119628. Epub 2010 Apr 28. J Biol Chem. 2010. PMID: 20427269 Free PMC article.
MicroRNA profile of circulating CD4-positive regulatory T cells in human adults and impact of differentially expressed microRNAs on expression of two genes essential to their function.
Fayyad-Kazan H, Rouas R, Fayyad-Kazan M, Badran R, El Zein N, Lewalle P, Najar M, Hamade E, Jebbawi F, Merimi M, Romero P, Burny A, Badran B, Martiat P. Fayyad-Kazan H, et al. J Biol Chem. 2012 Mar 23;287(13):9910-9922. doi: 10.1074/jbc.M111.337154. Epub 2012 Jan 31. J Biol Chem. 2012. PMID: 22294691 Free PMC article.
92 results