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Artificial selection for host resistance to tumour growth and subsequent cancer cell adaptations: an evolutionary arms race.
Ibrahim-Hashim A, Luddy K, Abrahams D, Enriquez-Navas P, Damgaci S, Yao J, Chen T, Bui MM, Gillies RJ, O'Farrelly C, Richards CL, Brown JS, Gatenby RA. Ibrahim-Hashim A, et al. Among authors: chen t. Br J Cancer. 2021 Jan;124(2):455-465. doi: 10.1038/s41416-020-01110-1. Epub 2020 Oct 7. Br J Cancer. 2021. PMID: 33024265 Free PMC article.
Acidity generated by the tumor microenvironment drives local invasion.
Estrella V, Chen T, Lloyd M, Wojtkowiak J, Cornnell HH, Ibrahim-Hashim A, Bailey K, Balagurunathan Y, Rothberg JM, Sloane BF, Johnson J, Gatenby RA, Gillies RJ. Estrella V, et al. Among authors: chen t. Cancer Res. 2013 Mar 1;73(5):1524-35. doi: 10.1158/0008-5472.CAN-12-2796. Epub 2013 Jan 3. Cancer Res. 2013. PMID: 23288510 Free PMC article.
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