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Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis.
Zhu L, Kamalathevan P, Koneva LA, Zarebska JM, Chanalaris A, Ismail H, Wiberg A, Ng M, Muhammad H, Walsby-Tickle J, McCullagh JSO, Watt FE; Oxford Hand Surgical Team; Sansom SN, Furniss D, Gardiner MD, Vincent TL, Riley N, Spiteri M, McNab I, Little C, Cogswell L, Critchley P, Giele H, Shirley R. Zhu L, et al. Sci Transl Med. 2022 Dec 21;14(676):eabm4054. doi: 10.1126/scitranslmed.abm4054. Epub 2022 Dec 21. Sci Transl Med. 2022. PMID: 36542696
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