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1,189 results

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Page 1
In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells.
Martinez-Lage M, Torres-Ruiz R, Puig-Serra P, Moreno-Gaona P, Martin MC, Moya FJ, Quintana-Bustamante O, Garcia-Silva S, Carcaboso AM, Petazzi P, Bueno C, Mora J, Peinado H, Segovia JC, Menendez P, Rodriguez-Perales S. Martinez-Lage M, et al. Among authors: mora j. Nat Commun. 2020 Oct 8;11(1):5060. doi: 10.1038/s41467-020-18875-x. Nat Commun. 2020. PMID: 33033246 Free PMC article.
Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma.
Taylor KR, Mackay A, Truffaux N, Butterfield Y, Morozova O, Philippe C, Castel D, Grasso CS, Vinci M, Carvalho D, Carcaboso AM, de Torres C, Cruz O, Mora J, Entz-Werle N, Ingram WJ, Monje M, Hargrave D, Bullock AN, Puget S, Yip S, Jones C, Grill J. Taylor KR, et al. Among authors: mora j. Nat Genet. 2014 May;46(5):457-461. doi: 10.1038/ng.2925. Epub 2014 Apr 6. Nat Genet. 2014. PMID: 24705252 Free PMC article.
The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin.
Ordóñez JL, Amaral AT, Carcaboso AM, Herrero-Martín D, del Carmen García-Macías M, Sevillano V, Alonso D, Pascual-Pasto G, San-Segundo L, Vila-Ubach M, Rodrigues T, Fraile S, Teodosio C, Mayo-Iscar A, Aracil M, Galmarini CM, Tirado OM, Mora J, de Álava E. Ordóñez JL, et al. Among authors: mora j. Oncotarget. 2015 Aug 7;6(22):18875-90. doi: 10.18632/oncotarget.4303. Oncotarget. 2015. PMID: 26056084 Free PMC article.
Cinacalcet inhibits neuroblastoma tumor growth and upregulates cancer-testis antigens.
Rodríguez-Hernández CJ, Mateo-Lozano S, García M, Casalà C, Briansó F, Castrejón N, Rodríguez E, Suñol M, Carcaboso AM, Lavarino C, Mora J, de Torres C. Rodríguez-Hernández CJ, et al. Among authors: mora j. Oncotarget. 2016 Mar 29;7(13):16112-29. doi: 10.18632/oncotarget.7448. Oncotarget. 2016. PMID: 26893368 Free PMC article.
Preclinical platform of retinoblastoma xenografts recapitulating human disease and molecular markers of dissemination.
Pascual-Pasto G, Olaciregui NG, Vila-Ubach M, Paco S, Monterrubio C, Rodriguez E, Winter U, Batalla-Vilacis M, Catala J, Salvador H, Parareda A, Schaiquevich P, Suñol M, Mora J, Lavarino C, de Torres C, Chantada GL, Carcaboso AM. Pascual-Pasto G, et al. Among authors: mora j. Cancer Lett. 2016 Sep 28;380(1):10-9. doi: 10.1016/j.canlet.2016.06.012. Epub 2016 Jun 16. Cancer Lett. 2016. PMID: 27319373
EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas.
Mohammad F, Weissmann S, Leblanc B, Pandey DP, Højfeldt JW, Comet I, Zheng C, Johansen JV, Rapin N, Porse BT, Tvardovskiy A, Jensen ON, Olaciregui NG, Lavarino C, Suñol M, de Torres C, Mora J, Carcaboso AM, Helin K. Mohammad F, et al. Among authors: mora j. Nat Med. 2017 Apr;23(4):483-492. doi: 10.1038/nm.4293. Epub 2017 Feb 27. Nat Med. 2017. PMID: 28263309
Targeted drug distribution in tumor extracellular fluid of GD2-expressing neuroblastoma patient-derived xenografts using SN-38-loaded nanoparticles conjugated to the monoclonal antibody 3F8.
Monterrubio C, Paco S, Olaciregui NG, Pascual-Pasto G, Vila-Ubach M, Cuadrado-Vilanova M, Ferrandiz MM, Castillo-Ecija H, Glisoni R, Kuplennik N, Jungbluth A, de Torres C, Lavarino C, Cheung NKV, Mora J, Sosnik A, Carcaboso AM. Monterrubio C, et al. Among authors: mora j. J Control Release. 2017 Jun 10;255:108-119. doi: 10.1016/j.jconrel.2017.04.016. Epub 2017 Apr 12. J Control Release. 2017. PMID: 28412222 Free PMC article.
Increased delivery of chemotherapy to the vitreous by inhibition of the blood-retinal barrier.
Pascual-Pasto G, Olaciregui NG, Opezzo JAW, Castillo-Ecija H, Cuadrado-Vilanova M, Paco S, Rivero EM, Vila-Ubach M, Restrepo-Perdomo CA, Torrebadell M, Suñol M, Schaiquevich P, Mora J, Bramuglia GF, Chantada GL, Carcaboso AM. Pascual-Pasto G, et al. Among authors: mora j. J Control Release. 2017 Oct 28;264:34-44. doi: 10.1016/j.jconrel.2017.08.018. Epub 2017 Aug 19. J Control Release. 2017. PMID: 28830790
1,189 results