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314 results

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Intracellular secretory leukoprotease inhibitor modulates inositol 1,4,5-triphosphate generation and exerts an anti-inflammatory effect on neutrophils of individuals with cystic fibrosis and chronic obstructive pulmonary disease.
Reeves EP, Banville N, Ryan DM, O'Reilly N, Bergin DA, Pohl K, Molloy K, McElvaney OJ, Alsaleh K, Aljorfi A, Kandalaft O, O'Flynn E, Geraghty P, O'Neill SJ, McElvaney NG. Reeves EP, et al. Among authors: mcelvaney oj, mcelvaney ng. Biomed Res Int. 2013;2013:560141. doi: 10.1155/2013/560141. Epub 2013 Aug 29. Biomed Res Int. 2013. PMID: 24073410 Free PMC article.
Galectin-9 signaling through TIM-3 is involved in neutrophil-mediated Gram-negative bacterial killing: an effect abrogated within the cystic fibrosis lung.
Vega-Carrascal I, Bergin DA, McElvaney OJ, McCarthy C, Banville N, Pohl K, Hirashima M, Kuchroo VK, Reeves EP, McElvaney NG. Vega-Carrascal I, et al. Among authors: mcelvaney oj, mcelvaney ng. J Immunol. 2014 Mar 1;192(5):2418-31. doi: 10.4049/jimmunol.1300711. Epub 2014 Jan 29. J Immunol. 2014. PMID: 24477913 Free PMC article. Clinical Trial.
A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy.
Pohl K, Hayes E, Keenan J, Henry M, Meleady P, Molloy K, Jundi B, Bergin DA, McCarthy C, McElvaney OJ, White MM, Clynes M, Reeves EP, McElvaney NG. Pohl K, et al. Among authors: mcelvaney oj, mcelvaney ng. Blood. 2014 Aug 14;124(7):999-1009. doi: 10.1182/blood-2014-02-555268. Epub 2014 Jun 16. Blood. 2014. PMID: 24934256 Free PMC article.
Inhaled hypertonic saline for cystic fibrosis: Reviewing the potential evidence for modulation of neutrophil signalling and function.
Reeves EP, McCarthy C, McElvaney OJ, Vijayan MS, White MM, Dunlea DM, Pohl K, Lacey N, McElvaney NG. Reeves EP, et al. Among authors: mcelvaney oj, mcelvaney ng. World J Crit Care Med. 2015 Aug 4;4(3):179-91. doi: 10.5492/wjccm.v4.i3.179. eCollection 2015 Aug 4. World J Crit Care Med. 2015. PMID: 26261770 Free PMC article. Review.
Neutrophil Membrane Cholesterol Content is a Key Factor in Cystic Fibrosis Lung Disease.
White MM, Geraghty P, Hayes E, Cox S, Leitch W, Alfawaz B, Lavelle GM, McElvaney OJ, Flannery R, Keenan J, Meleady P, Henry M, Clynes M, Gunaratnam C, McElvaney NG, Reeves EP. White MM, et al. Among authors: mcelvaney oj, mcelvaney ng. EBioMedicine. 2017 Sep;23:173-184. doi: 10.1016/j.ebiom.2017.08.013. Epub 2017 Aug 16. EBioMedicine. 2017. PMID: 28835336 Free PMC article.
Glycosylation Repurposes Alpha-1 Antitrypsin for Resolution of Community-acquired Pneumonia.
McCarthy C, Dunlea DM, Saldova R, Henry M, Meleady P, McElvaney OJ, Marsh B, Rudd PM, Reeves EP, McElvaney NG. McCarthy C, et al. Among authors: mcelvaney oj, mcelvaney ng. Am J Respir Crit Care Med. 2018 May 15;197(10):1346-1349. doi: 10.1164/rccm.201709-1954LE. Am J Respir Crit Care Med. 2018. PMID: 29144158 No abstract available.
314 results