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Safety, pharmacokinetics and pharmacodynamics of BI 705564, a highly selective, covalent inhibitor of Bruton's tyrosine kinase, in Phase I clinical trials in healthy volunteers.
Litzenburger T, Steffgen J, Benediktus E, Müller F, Schultz A, Klein E, Ramanujam M, Harcken C, Gupta A, Wu J, Wiebe S, Li X, Flack M, Padula SJ, Visvanathan S, Hünnemeyer A, Hui J. Litzenburger T, et al. Among authors: benediktus e. Br J Clin Pharmacol. 2021 Apr;87(4):1824-1838. doi: 10.1111/bcp.14571. Epub 2020 Nov 20. Br J Clin Pharmacol. 2021. PMID: 32986868 Free PMC article. Clinical Trial.
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Novel CRTH2 Antagonist BI 1021958 at Single Oral Doses in Healthy Men and Multiple Oral Doses in Men and Women With Well-Controlled Asthma.
Fowler A, Koenen R, Hilbert J, Blatchford J, Kappeler D, Benediktus E, Wood C, Gupta A. Fowler A, et al. Among authors: benediktus e. J Clin Pharmacol. 2017 Nov;57(11):1444-1453. doi: 10.1002/jcph.947. Epub 2017 Jun 13. J Clin Pharmacol. 2017. PMID: 28609567 Clinical Trial.
Pharmacogenomics of asthma.
Pahl A, Benediktus E, Chialda L. Pahl A, et al. Among authors: benediktus e. Curr Pharm Des. 2006;12(25):3195-206. doi: 10.2174/138161206778194105. Curr Pharm Des. 2006. PMID: 17020528 Review.