Li X - Search Results

1

Structure-guided modification of isoxazole-type FXR agonists: Identification of a potent and orally bioavailable FXR modulator.

Luo G, Lin X, Li Z, Xiao M, Li X, Zhang D, Xiang H. Luo G, et al. Among authors: li z, li x. Eur J Med Chem. 2021 Jan 1;209:112910. doi: 10.1016/j.ejmech.2020.112910. Epub 2020 Oct 7. Eur J Med Chem. 2021. PMID: 33049605

2

Novel SERMs based on 3-aryl-4-aryloxy-2H-chromen-2-one skeleton - A possible way to dual ERα/VEGFR-2 ligands for treatment of breast cancer.

Luo G, Li X, Zhang G, Wu C, Tang Z, Liu L, You Q, Xiang H. Luo G, et al. Among authors: li x. Eur J Med Chem. 2017 Nov 10;140:252-273. doi: 10.1016/j.ejmech.2017.09.015. Epub 2017 Sep 14. Eur J Med Chem. 2017. PMID: 28942113

3

Synthesis and activity towards Alzheimer's disease in vitro: Tacrine, phenolic acid and ligustrazine hybrids.

Li G, Hong G, Li X, Zhang Y, Xu Z, Mao L, Feng X, Liu T. Li G, et al. Among authors: li x. Eur J Med Chem. 2018 Mar 25;148:238-254. doi: 10.1016/j.ejmech.2018.01.028. Epub 2018 Feb 13. Eur J Med Chem. 2018. PMID: 29466774

4

Synthesis and biological evaluation of 4,6-diaryl-2-pyrimidinamine derivatives as anti-breast cancer agents.

Liu L, Tang Z, Wu C, Li X, Huang A, Lu X, You Q, Xiang H. Liu L, et al. Among authors: li x. Bioorg Med Chem Lett. 2018 Apr 1;28(6):1138-1142. doi: 10.1016/j.bmcl.2017.12.066. Epub 2017 Dec 30. Bioorg Med Chem Lett. 2018. PMID: 29482944

5

Structure-activity relationships of 2, 4-disubstituted pyrimidines as dual ERα/VEGFR-2 ligands with anti-breast cancer activity.

Luo G, Tang Z, Lao K, Li X, You Q, Xiang H. Luo G, et al. Among authors: li x. Eur J Med Chem. 2018 Apr 25;150:783-795. doi: 10.1016/j.ejmech.2018.03.018. Epub 2018 Mar 7. Eur J Med Chem. 2018. PMID: 29587221

6

Lipid accumulation inhibitory activities of novel isoxazole-based chenodeoxycholic acids: Design, synthesis and preliminary mechanism study.

Qiu R, Luo G, Li X, Zheng F, Li H, Zhang J, You Q, Xiang H. Qiu R, et al. Among authors: li x, li h. Bioorg Med Chem Lett. 2018 Sep 15;28(17):2879-2884. doi: 10.1016/j.bmcl.2018.07.026. Epub 2018 Jul 17. Bioorg Med Chem Lett. 2018. PMID: 30031618

7

Design and synthesis of benzofuro[3,2-b]pyridin-2(1H)-one derivatives as anti-leukemia agents by inhibiting Btk and PI3Kδ.

Liu L, Shi B, Li X, Wang X, Lu X, Cai X, Huang A, Luo G, You Q, Xiang H. Liu L, et al. Among authors: li x. Bioorg Med Chem. 2018 Aug 15;26(15):4537-4543. doi: 10.1016/j.bmc.2018.07.047. Epub 2018 Jul 29. Bioorg Med Chem. 2018. PMID: 30077608

8

Synthesis and biological evaluation of 3-aryl-quinolin derivatives as anti-breast cancer agents targeting ERα and VEGFR-2.

Li X, Wu C, Lin X, Cai X, Liu L, Luo G, You Q, Xiang H. Li X, et al. Eur J Med Chem. 2019 Jan 1;161:445-455. doi: 10.1016/j.ejmech.2018.10.045. Epub 2018 Oct 19. Eur J Med Chem. 2019. PMID: 30384047

9

Optimization of novel benzofuro[3,2-b]pyridin-2(1H)-one derivatives as dual inhibitors of BTK and PI3Kδ.

Liu L, Li X, Cheng Y, Wang L, Yang H, Li J, He S, Shuangjie Wu, Yin Q, Xiang H. Liu L, et al. Among authors: li j, li x. Eur J Med Chem. 2019 Feb 15;164:304-316. doi: 10.1016/j.ejmech.2018.12.055. Epub 2018 Dec 26. Eur J Med Chem. 2019. PMID: 30605829

10

3, 9-di-O-substituted coumestrols incorporating basic amine side chains act as novel apoptosis inducers with improved pharmacological selectivity.

Luo G, Tang Z, Li X, Hou Q, Chen Y, Lao K, Xiang H. Luo G, et al. Among authors: li x. Bioorg Chem. 2019 Apr;85:140-151. doi: 10.1016/j.bioorg.2018.12.024. Epub 2018 Dec 22. Bioorg Chem. 2019. PMID: 30612080

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