Owens RA - Search Results

1

Targeting Methionine Synthase in a Fungal Pathogen Causes a Metabolic Imbalance That Impacts Cell Energetics, Growth, and Virulence.

Scott J, Sueiro-Olivares M, Thornton BP, Owens RA, Muhamadali H, Fortune-Grant R, Thomson D, Thomas R, Hollywood K, Doyle S, Goodacre R, Tabernero L, Bignell E, Amich J. Scott J, et al. Among authors: owens ra. mBio. 2020 Oct 13;11(5):e01985-20. doi: 10.1128/mBio.01985-20. mBio. 2020. PMID: 33051366 Free PMC article.

2

Molecular characterization of an adaptive response to alkylating agents in the opportunistic pathogen Aspergillus fumigatus.

O'Hanlon KA, Margison GP, Hatch A, Fitzpatrick DA, Owens RA, Doyle S, Jones GW. O'Hanlon KA, et al. Among authors: owens ra. Nucleic Acids Res. 2012 Sep;40(16):7806-20. doi: 10.1093/nar/gks522. Epub 2012 Jun 4. Nucleic Acids Res. 2012. PMID: 22669901 Free PMC article.

3

The Aspergillus fumigatus protein GliK protects against oxidative stress and is essential for gliotoxin biosynthesis.

Gallagher L, Owens RA, Dolan SK, O'Keeffe G, Schrettl M, Kavanagh K, Jones GW, Doyle S. Gallagher L, et al. Among authors: owens ra. Eukaryot Cell. 2012 Oct;11(10):1226-38. doi: 10.1128/EC.00113-12. Epub 2012 Aug 17. Eukaryot Cell. 2012. PMID: 22903976 Free PMC article.

4

Regulation of nonribosomal peptide synthesis: bis-thiomethylation attenuates gliotoxin biosynthesis in Aspergillus fumigatus.

Dolan SK, Owens RA, O'Keeffe G, Hammel S, Fitzpatrick DA, Jones GW, Doyle S. Dolan SK, et al. Among authors: owens ra. Chem Biol. 2014 Aug 14;21(8):999-1012. doi: 10.1016/j.chembiol.2014.07.006. Chem Biol. 2014. PMID: 25126990

5

A proteomic approach to investigating gene cluster expression and secondary metabolite functionality in Aspergillus fumigatus.

Owens RA, Hammel S, Sheridan KJ, Jones GW, Doyle S. Owens RA, et al. PLoS One. 2014 Sep 8;9(9):e106942. doi: 10.1371/journal.pone.0106942. eCollection 2014. PLoS One. 2014. PMID: 25198175 Free PMC article.

6

RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus.

O'Keeffe G, Hammel S, Owens RA, Keane TM, Fitzpatrick DA, Jones GW, Doyle S. O'Keeffe G, et al. Among authors: owens ra. BMC Genomics. 2014 Oct 14;15(1):894. doi: 10.1186/1471-2164-15-894. BMC Genomics. 2014. PMID: 25311525 Free PMC article.

7

Impact of the antifungal protein PgAFP from Penicillium chrysogenum on the protein profile in Aspergillus flavus.

Delgado J, Owens RA, Doyle S, Asensio MA, Núñez F. Delgado J, et al. Among authors: owens ra. Appl Microbiol Biotechnol. 2015 Oct;99(20):8701-15. doi: 10.1007/s00253-015-6731-x. Epub 2015 Jun 16. Appl Microbiol Biotechnol. 2015. PMID: 26078108

8

Interplay between Gliotoxin Resistance, Secretion, and the Methyl/Methionine Cycle in Aspergillus fumigatus.

Owens RA, O'Keeffe G, Smith EB, Dolan SK, Hammel S, Sheridan KJ, Fitzpatrick DA, Keane TM, Jones GW, Doyle S. Owens RA, et al. Eukaryot Cell. 2015 Sep;14(9):941-57. doi: 10.1128/EC.00055-15. Epub 2015 Jul 6. Eukaryot Cell. 2015. PMID: 26150413 Free PMC article.

9

Increased chitin biosynthesis contributes to the resistance of Penicillium polonicum against the antifungal protein PgAFP.

Delgado J, Owens RA, Doyle S, Asensio MA, Núñez F. Delgado J, et al. Among authors: owens ra. Appl Microbiol Biotechnol. 2016 Jan;100(1):371-83. doi: 10.1007/s00253-015-7020-4. Epub 2015 Oct 8. Appl Microbiol Biotechnol. 2016. PMID: 26446386

10

The iron-responsive microsomal proteome of Aspergillus fumigatus.

Moloney NM, Owens RA, Meleady P, Henry M, Dolan SK, Mulvihill E, Clynes M, Doyle S. Moloney NM, et al. Among authors: owens ra. J Proteomics. 2016 Mar 16;136:99-111. doi: 10.1016/j.jprot.2015.12.025. Epub 2015 Dec 29. J Proteomics. 2016. PMID: 26739764

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