Schormann N - Search Results

1

Chlamydia trachomatis glyceraldehyde 3-phosphate dehydrogenase: Enzyme kinetics, high-resolution crystal structure, and plasminogen binding.

Schormann N, Campos J, Motamed R, Hayden KL, Gould JR, Green TJ, Senkovich O, Banerjee S, Ulett GC, Chattopadhyay D. Schormann N, et al. Protein Sci. 2020 Dec;29(12):2446-2458. doi: 10.1002/pro.3975. Epub 2020 Oct 30. Protein Sci. 2020. PMID: 33058314 Free PMC article.

2

Expression, purification, crystallization and preliminary crystallographic analysis of recombinant pteridine reductase of Trypanosoma cruzi.

Schormann N, Pal B, Chattopadhyay D. Schormann N, et al. Acta Crystallogr D Biol Crystallogr. 2001 Nov;57(Pt 11):1671-3. doi: 10.1107/s0907444901012094. Epub 2001 Oct 25. Acta Crystallogr D Biol Crystallogr. 2001. PMID: 11679740

3

Trypanosoma cruzi genome encodes a pteridine reductase 2 protein.

Senkovich O, Pal B, Schormann N, Chattopadhyay D. Senkovich O, et al. Among authors: schormann n. Mol Biochem Parasitol. 2003 Mar;127(1):89-92. doi: 10.1016/s0166-6851(02)00309-2. Mol Biochem Parasitol. 2003. PMID: 12615341 No abstract available.

4

Crystal structure of Trypanosoma cruzi pteridine reductase 2 in complex with a substrate and an inhibitor.

Schormann N, Pal B, Senkovich O, Carson M, Howard A, Smith C, Delucas L, Chattopadhyay D. Schormann N, et al. J Struct Biol. 2005 Oct;152(1):64-75. doi: 10.1016/j.jsb.2005.07.008. J Struct Biol. 2005. PMID: 16168672

5

Structures of vaccinia virus dUTPase and its nucleotide complexes.

Samal A, Schormann N, Cook WJ, DeLucas LJ, Chattopadhyay D. Samal A, et al. Among authors: schormann n. Acta Crystallogr D Biol Crystallogr. 2007 May;63(Pt 5):571-80. doi: 10.1107/S0907444907007871. Epub 2007 Apr 21. Acta Crystallogr D Biol Crystallogr. 2007. PMID: 17452782

6

Crystal structure of vaccinia virus uracil-DNA glycosylase reveals dimeric assembly.

Schormann N, Grigorian A, Samal A, Krishnan R, DeLucas L, Chattopadhyay D. Schormann N, et al. BMC Struct Biol. 2007 Jul 2;7:45. doi: 10.1186/1472-6807-7-45. BMC Struct Biol. 2007. PMID: 17605817 Free PMC article.

7

Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function.

Schormann N, Senkovich O, Walker K, Wright DL, Anderson AC, Rosowsky A, Ananthan S, Shinkre B, Velu S, Chattopadhyay D. Schormann N, et al. Proteins. 2008 Dec;73(4):889-901. doi: 10.1002/prot.22115. Proteins. 2008. PMID: 18536013

8

Structures of dihydrofolate reductase-thymidylate synthase of Trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate.

Senkovich O, Schormann N, Chattopadhyay D. Senkovich O, et al. Among authors: schormann n. Acta Crystallogr D Biol Crystallogr. 2009 Jul;65(Pt 7):704-16. doi: 10.1107/S090744490901230X. Epub 2009 Jun 20. Acta Crystallogr D Biol Crystallogr. 2009. PMID: 19564691

9

Synthesis and characterization of potent inhibitors of Trypanosoma cruzi dihydrofolate reductase.

Schormann N, Velu SE, Murugesan S, Senkovich O, Walker K, Chenna BC, Shinkre B, Desai A, Chattopadhyay D. Schormann N, et al. Bioorg Med Chem. 2010 Jun 1;18(11):4056-66. doi: 10.1016/j.bmc.2010.04.020. Epub 2010 Apr 9. Bioorg Med Chem. 2010. PMID: 20452776

10

Identification of inhibitors that block vaccinia virus infection by targeting the DNA synthesis processivity factor D4.

Nuth M, Huang L, Saw YL, Schormann N, Chattopadhyay D, Ricciardi RP. Nuth M, et al. Among authors: schormann n. J Med Chem. 2011 May 12;54(9):3260-7. doi: 10.1021/jm101554k. Epub 2011 Apr 19. J Med Chem. 2011. PMID: 21438571 Free PMC article.

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