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Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription.
Rimel JK, Poss ZC, Erickson B, Maas ZL, Ebmeier CC, Johnson JL, Decker TM, Yaron TM, Bradley MJ, Hamman KB, Hu S, Malojcic G, Marineau JJ, White PW, Brault M, Tao L, DeRoy P, Clavette C, Nayak S, Damon LJ, Kaltheuner IH, Bunch H, Cantley LC, Geyer M, Iwasa J, Dowell RD, Bentley DL, Old WM, Taatjes DJ. Rimel JK, et al. Among authors: old wm. Genes Dev. 2020 Nov 1;34(21-22):1452-1473. doi: 10.1101/gad.341545.120. Epub 2020 Oct 15. Genes Dev. 2020. PMID: 33060135 Free PMC article.
Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications.
Ebmeier CC, Erickson B, Allen BL, Allen MA, Kim H, Fong N, Jacobsen JR, Liang K, Shilatifard A, Dowell RD, Old WM, Bentley DL, Taatjes DJ. Ebmeier CC, et al. Among authors: old wm. Cell Rep. 2017 Aug 1;20(5):1173-1186. doi: 10.1016/j.celrep.2017.07.021. Cell Rep. 2017. PMID: 28768201 Free PMC article.
Changes to the TDP-43 and FUS Interactomes Induced by DNA Damage.
Kawaguchi T, Rollins MG, Moinpour M, Morera AA, Ebmeier CC, Old WM, Schwartz JC. Kawaguchi T, et al. Among authors: old wm. J Proteome Res. 2020 Jan 3;19(1):360-370. doi: 10.1021/acs.jproteome.9b00575. Epub 2019 Dec 2. J Proteome Res. 2020. PMID: 31693373 Free PMC article.
Multiomic Analysis Reveals Disruption of Cholesterol Homeostasis by Cannabidiol in Human Cell Lines.
Guard SE, Chapnick DA, Poss ZC, Ebmeier CC, Jacobsen J, Nemkov T, Ball KA, Webb KJ, Simpson HL, Coleman S, Bunker E, Ramirez A, Reisz JA, Sievers R, Stowell MHB, D'Alessandro A, Liu X, Old WM. Guard SE, et al. Among authors: old wm. Mol Cell Proteomics. 2022 Oct;21(10):100262. doi: 10.1016/j.mcpro.2022.100262. Epub 2022 Jun 24. Mol Cell Proteomics. 2022. PMID: 35753663 Free PMC article.
58 results